CD48 Protein (CD48) (Fc Tag)

Catalog No. ABIN7536139

Product Details

Target: CD48

Protein Type: Recombinant

Biological Activity: Active

Origin: Mouse

Source: HEK-293 Cells

Purification tag / Conjugate: This CD48 protein is labelled with Fc Tag.

Purpose: Active Recombinant Mouse SLAMF2/CD48 Protein

Sequence: FQGHSIPDIN ATTGSNVTLK IHKDPLGPYK RITWLHTKNQ KILEYNYNST KTIFESEFKG RVYLEENNGA LHISNVRKED KGTYYMRVLR ETENELKITL EVFDPVPKPS IEINKTEAST DSCHLRLSCE VKDQHVDYTW YESSGPFPKK SPGYVLDLIV TPQNKSTFYT CQVSNPVSSK NDTVYFTLPC DLAR

Specificity: Phe23-Arg216

Purity: > 95 % by SDS-PAGE.

Sterility: 0.22 μm filtered

Endotoxin Level: <0.1EU/μg

Biological Activity Comment: Measured by its binding ability in a functional ELISA. Immobilized Human CD48 at 10 μg/mL (100 μL/well) can bind Human CD224 with a linear range of 0.87-18.4 ng/mL.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.

Buffer: Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.

Storage: -20 °C,-80 °C

Storage Comment: Store the lyophilized protein at -20°C to -80°C for 12 months.|After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.

Target Details

Target: CD48

Alternative Name: SLAMF2/CD48 (CD48 Products)

Synonyms: AI449234 Protein, AW610730 Protein, BCM1 Protein, BLAST Protein, BLAST-1 Protein, BLAST1 Protein, Bcm-1 Protein, MEM-102 Protein, SLAMF2 Protein, Sgp-60 Protein, hCD48 Protein, mCD48 Protein, CD48 antigen Protein, Cd48 molecule Protein, CD48 molecule Protein, Cd48 Protein, CD48 Protein

Background:

Description: This protein is a member of the CD2 subfamily of immunoglobulin-like receptors which includes SLAM (signaling lymphocyte activation molecules) proteins. The encoded protein is found on the surface of lymphocytes and other immune cells, dendritic cells and endothelial cells, and participates in activation and differentiation pathways in these cells. The encoded protein does not have a transmembrane domain, however, but is held at the cell surface by a GPI anchor via a C-terminal domain which maybe cleaved to yield a soluble form of the receptor. Multiple transcript variants encoding different isoforms have been found for this gene.

Name: BCM1,BLAST,BLAST1,hCD48,mCD48,MEM-102,SLAMF2,CD48

Gene ID: 12506

UniProt: P18181