Oncostatin M Protein (OSM) (His tag)
Quick Overview for Oncostatin M Protein (OSM) (His tag) (ABIN7536079)
Target
See all Oncostatin M (OSM) ProteinsProtein Type
Origin
Source
Purity
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Purification tag / Conjugate
- This Oncostatin M protein is labelled with His tag.
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Purpose
- Recombinant Mouse Oncostatin-M/OSM Protein
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Sequence
- MQTRLLRTLL SLTLSLLILS MALANRGCSN SSSQLLSQLQ NQANLTGNTE SLLEPYIRLQ NLNTPDLRAA CTQHSVAFPS EDTLRQLSKP HFLSTVYTTL DRVLYQLDAL RQKFLKTPAF PKLDSARHNI LGIRNNVFCM ARLLNHSLEI PEPTQTDSGA SRSTTTPDVF NTKIGSCGFL WGYHRFMGSV GRVFREWDDG STRSRR
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Specificity
- Met 1-Arg 206
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Sterility
- 0.22 μm filtered
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Endotoxin Level
- <0.1EU/μg
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Oncostatin M (OSM) (AA 26-221) protein (His-Avi Tag)
OSM Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Oncostatin M (OSM) (AA 25-206) protein (His tag)OSM Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Oncostatin M (OSM) (AA 26-221) protein (His-Avi Tag,Biotin)OSM Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Oncostatin M (OSM) (AA 26-239) protein (His-IF2DI Tag)OSM Origin: Rat Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Oncostatin M (OSM) (AA 26-221) (Active) protein (His tag)OSM Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA Active
Oncostatin M (OSM) protein (His tag)OSM Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by reducing SDS-PAGE.
Oncostatin M (OSM) (AA 1-252) protein (GST tag)OSM Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Oncostatin M (OSM) (AA 26-234) protein (His tag)OSM Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % by SDS - PAGE SDS
Oncostatin M (OSM) (AA 26-252) proteinOSM Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
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Buffer
- Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
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Storage
- -20 °C,-80 °C
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Storage Comment
- Store the lyophilized protein at -20°C to -80°C for 12 months.|After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.
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- Oncostatin M (OSM)
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Alternative Name
- Oncostatin-M/OSM
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Background
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Description: OSM is a pleiotropic cytokine that initiates its biological activities by binding to specific cell surface receptors. Inhibits the proliferation of a number of tumor cell lines. Stimulates proliferation of AIDS-KS cells. It regulates cytokine production, including IL-6, G-CSF and GM-CSF from endothelial cells. Uses both type I OSM receptor (heterodimers composed of LIFR and IL6ST) and type II OSM receptor (heterodimers composed of OSMR and IL6ST). Involved in the maturation of fetal hepatocytes, thereby promoting liver development and regeneration.
Name: OncoM,OSM
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Gene ID
- 18413
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UniProt
- P53347
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Pathways
- JAK-STAT Signaling, Negative Regulation of Hormone Secretion
Target
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