WFDC1 Protein (AA 32-220) (Fc Tag)

Catalog No. ABIN7538590

Product Details

Target: WFDC1 (WAP Four-Disulfide Core Domain 1 (WFDC1))

Protein Type: Recombinant

Protein Characteristics: AA 32-220

Origin: Human

Source: Mammalian Cells

Purification tag / Conjugate: This WFDC1 protein is labelled with Fc Tag.

Purpose: Recombinant Human WFDC1 Protein with C-terminal human Fc tag

Specificity: WFDC1 (Lys32-Gln220) hFc (Glu99-Ala330)

Characteristics: Extracellular Domain Protein

Purification: Purified from cell culture supernatant by affinity chromatography

Purity: The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Storage: -20 °C,-80 °C

Storage Comment: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Expiry Date: 12 months

Target Details

Target: WFDC1 (WAP Four-Disulfide Core Domain 1 (WFDC1))

Alternative Name: WFDC1 (WFDC1 Products)

Background: This gene encodes a member of the WAP-type four disulfide core domain family. The WAP-type four-disulfide core domain contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor in many family members. This gene is mapped to chromosome 16q24, an area of frequent loss of heterozygosity in cancers, including prostate, breast and hepatocellular cancers and Wilms' tumor. This gene is downregulated in many cancer types and may be involved in the inhibition of cell proliferation. The encoded protein may also play a role in the susceptibility of certain CD4 memory T cells to human immunodeficiency virus infection. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]

Molecular Weight: predicted molecular mass of 46.9 kDa after removal of the signal peptide. The apparent molecular mass of WFDC1-hFc is 55-70 kDa due to glycosylation.

UniProt: Q9HC57