WFDC1 Protein (AA 32-220) (His tag)
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- Target See all WFDC1 Proteins
- WFDC1 (WAP Four-Disulfide Core Domain 1 (WFDC1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 32-220
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This WFDC1 protein is labelled with His tag.
- Purpose
- Human PS20 Protein
- Sequence
- Lys32-Gln220
- Characteristics
- Recombinant Human PS20 Protein is expressed from E.coli with His tag at the N-Terminus.It contains Lys32-Gln220.
- Purity
- > 95 % as determined by Tris-Bis PAGE
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
- Top Product
- Discover our top product WFDC1 Protein
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WAP Four-Disulfide Core Domain 1 (WFDC1) (AA 24-211) protein (His tag)
WFDC1 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
WAP Four-Disulfide Core Domain 1 (WFDC1) (AA 32-192) protein (His tag)WFDC1 Origin: Cynomolgus Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by Tris-Bis PAGE
WAP Four-Disulfide Core Domain 1 (WFDC1) (AA 121-220) protein (GST tag)WFDC1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
WAP Four-Disulfide Core Domain 1 (WFDC1) protein (Myc-DYKDDDDK Tag)WFDC1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
WAP Four-Disulfide Core Domain 1 (WFDC1) protein (DYKDDDDK-His Tag)WFDC1 Origin: Mouse Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Supplied as 0.22μm filtered solution in 20 mM PB, 500 mM NaCl, 200 mM L-arginine ( pH 7.4).
- Storage
- -80 °C
- Storage Comment
- Valid for 12 months from date of receipt when stored at -80°C., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- WFDC1 (WAP Four-Disulfide Core Domain 1 (WFDC1))
- Alternative Name
- PS20 (WFDC1 Products)
- Synonyms
- WFDC1 Protein, zgc:158671 Protein, PS20 Protein, 2310058A03Rik Protein, ps20 Protein, WAP four-disulfide core domain 1 Protein, WFDC1 Protein, wfdc1 Protein, Wfdc1 Protein
- Background
- The whey acidic protein family member, WFDC1/ps20 is a permissivity factor in HIV infection. Herein we describe a contrasting role for ps20 in limiting MHV-1 infection. Intranasal MHV-1 infection produces a respiratory infection in mice. Using ps20 knockout mice we provide evidence that intranasal MHV-1 infection results in increased lung viral titers in ps20(-/-) compared to ps20(/) mice. Roles for ps20 in regulating expression of neutrophil-specific chemotactic factors, thereby potentially modulating neutrophil migration, and in modulating neutrophil susceptibility to MHV-1 infection.
- Molecular Weight
- 22 kDa. The protein migrates to 25-30 kDa based on Tris-Bis PAGE result.
- UniProt
- Q9HC57
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