PLEKHM3 Protein (AA 1-761) (His tag)

Catalog No. ABIN7558752

Recombinant PLEKHM3 protein expressed in HEK-293 Cells.

Quick Overview for PLEKHM3 Protein (AA 1-761) (His tag) (ABIN7558752)

Target: PLEKHM3 (Pleckstrin Homology Domain Containing, Family M, Member 3 (PLEKHM3))

Protein Type: Recombinant

Origin: Mouse

Source: HEK-293 Cells

Purity: > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

Grade: custom-made

Product Details

Protein Characteristics: AA 1-761

Purification tag / Conjugate: This PLEKHM3 protein is labelled with His tag.

Purpose: Predefined custom protein recombinant Plekhm3 Protein expressed in mammalian cells.

Sequence: MEALEVDDIS PALEVTEDFF STFDSKLEKA VQQAEVYGIQ EVPELVGHEV LGNIADNGAL RSVASLGKGT MIWDHCKSRL LETKAQNVFP AKEQLMVQRG TAPDNLSWMA QKEASTFNFF NICQRRRDRP RSVNDLLDET TTFKPGHARS RSDVTHVDWR VVLSTMPLQQ QQQQQQASLQ GIHFPGPSFL LSSPSKVEDA QGNTEHKQTF PNILKKGYLE IRKNHDSYWQ SCYAELSPYN LNFYSLDSSG NQNLYATYQL SHFQSISVLG NLEARMVDTV LYDNSQLQLK AESPWEALDW GQKLWEVVHA AVPNYMGRQG EMANSPGLIH HGDCAQNHCL QKKSSGLLAS PVLDSPKQYQ NILKSGTLYR LTVQNNWKAF TFVLSKAYLM AFHPGKLDED PLLSYNVDVC LAVQIDNLDG CDSCFQVIFP QDVLRLRAET RQRAQEWMEA LKTAANAARS SEQNLQVTLR NKPKDQLDGR ELRKNKRQSV TTSFLSILTT LSLERGLTAQ SFKCAGCQRS IGLSNGKAKV CNYSGWYYCS SCHVDDSFLI PARIVHNWDT SKYKVSKQAK EFLEYVYEEP LIDIQQENPM LYLHAEPLAT VVRLRQRLKS LRAYLFSCRA AVAEDLRRRI FPREYLLQQI HLYSLADLQQ VIEGKLAPFL GKVIKFATAH VYSCSLCSQK GFICEICNNG EILYPFEDIS TSRCESCGAV FHSECKEKSV PCPRCVRREL QKKQKSFWRQ LNVDESLEEA CAMFELSYQS T Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.

Specificity: If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.

Characteristics: Key Benefits:

• Predefined custom protein - from design to production - by highly experienced protein experts.
• Protein expressed in mammalian cells and purified in one-step affinity chromatography
• The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
• State-of-the-art algorithm used for plasmid design (Gene synthesis).

This protein is a predefined protein and will be made for the first time for your order. Our experts in the lab try to ensure that you receive soluble protein.

If you are not interested in a full length protein, please contact us for individual protein fragments.

The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.

Application Details

Application Notes: We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The buffer composition is at the discretion of the manufacturer.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -80 °C

Storage Comment: Store at -80°C.

Expiry Date: 12 months

Target Details

Target: PLEKHM3 (Pleckstrin Homology Domain Containing, Family M, Member 3 (PLEKHM3))

Alternative Name: Plekhm3

Background: Pleckstrin homology domain-containing family M member 3 (PH domain-containing family M member 3) (Differentiation-associated protein),FUNCTION: Involved in skeletal muscle differentiation (PubMed:19028694). May act as a scaffold protein for AKT1 during muscle differentiation (PubMed:19028694). {ECO:0000269|PubMed:19028694}.

Molecular Weight: 86.6 kDa

UniProt: Q8BM47

AlphaFold: Q8BM47