ACE2 Protein (AA 18-740) (His tag)
Quick Overview for ACE2 Protein (AA 18-740) (His tag) (ABIN7677525)
Target
See all ACE2 ProteinsProtein Type
Biological Activity
Origin
Source
Application
Purity
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Protein Characteristics
- AA 18-740
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Purification tag / Conjugate
- This ACE2 protein is labelled with His tag.
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Sequence
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QSLTEENAKT FLNNFNQEAE DLSYQSSLAS WNYNTNITEE NAQKMSEAAA KWSAFYEEQS KTAQSFSLQE IQTPIIKRQL QALQQSGSSA LSADKNKQLN TILNTMSTIY STGKVCNPKN PQECLLLEPG LDEIMATSTD YNSRLWAWEG WRAEVGKQLR PLYEEYVVLK NEMARANNYN DYGDYWRGDY EAEGADGYNY NRNQLIEDVE RTFAEIKPLY EHLHAYVRRK LMDTYPSYIS PTGCLPAHLL GDMWGRFWTN LYPLTVPFAQ KPNIDVTDAM MNQGWDAERI FQEAEKFFVS VGLPHMTQGF WANSMLTEPA DGRKVVCHPT AWDLGHGDFR IKMCTKVTMD NFLTAHHEMG HIQYDMAYAR QPFLLRNGAN EGFHEAVGEI MSLSAATPKH LKSIGLLPSD FQEDSETEIN FLLKQALTIV GTLPFTYMLE KWRWMVFRGE IPKEQWMKKW WEMKREIVGV VEPLPHDETY CDPASLFHVS NDYSFIRYYT RTIYQFQFQE ALCQAAKYNG SLHKCDISNS TEAGQKLLKM LSLGNSEPWT KALENVVGAR NMDVKPLLNY FQPLFDWLKE QNRNSFVGWN TEWSPYADQS IKVRISLKSA LGANAYEWTN NEMFLFRSSV AYAMRKYFSI IKNQTVPFLE EDVRVSDLKP RVSFYFFVTS PQNVSDVIPR SEVEDAIRMS RGRINDVFGL NDNSLEFLGI HPTLEPPYQP PVT
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Purification
- > 95% by SDS-PAGE
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Endotoxin Level
- < 1 EU per 1ug of protein (determined by LAL method)
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Biological Activity Comment
- Specific activity is > 200 pmol/min/ug, and is defined as the amount of enzyme that hydrolysis 1.0 pmole of Mca-YVADAPK(Dnp)-OH per minute at pH 7.5, at 25C.
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Angiotensin I Converting Enzyme 2 (ACE2) protein (His tag,AVI tag,Biotin)
ACE2 Origin: Human Host: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. SDS, Func
Angiotensin I Converting Enzyme 2 (ACE2) protein (His tag)ACE2 Origin: Paguma larvata Host: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. SDS
Angiotensin I Converting Enzyme 2 (ACE2) (AA 18-740) (Active) protein (Biotin,His-Avi Tag)ACE2 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Angiotensin I Converting Enzyme 2 (ACE2) (AA 18-739) (Active) protein (His-Avi Tag)ACE2 Origin: Cynomolgus Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Angiotensin I Converting Enzyme 2 (ACE2) (AA 18-740) (Active) protein (His-Avi Tag)ACE2 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Angiotensin I Converting Enzyme 2 (ACE2) (AA 18-740) (Active) protein (hFc-Avi Tag,Biotin)ACE2 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE Active
Angiotensin I Converting Enzyme 2 (ACE2) (Active) protein (His tag)ACE2 Origin: Rhesus Monkey Host: Human Cells Recombinant >95 % as determined by reducing SDS-PAGE. Active
Angiotensin I Converting Enzyme 2 (ACE2) (Active) protein (Fc Tag)ACE2 Origin: Rhesus Monkey Host: Human Cells Recombinant >95 % as determined by reducing SDS-PAGE. Active
Angiotensin I Converting Enzyme 2 (ACE2) (AA 18-740) (Active) protein (Fc Tag)ACE2 Origin: Human Host: HEK-293 Cells Recombinant > 95 % by SDS-PAGE. SDS, Func Active
Angiotensin I Converting Enzyme 2 (ACE2) (AA 18-740) protein (His tag)ACE2 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. AM, ADA, IA, ScA
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Phosphate-Buffered Saline ( pH 7.4) containing 10 % glycerol
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Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
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- ACE2 (Angiotensin I Converting Enzyme 2 (ACE2))
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Alternative Name
- ACE-2
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Background
- ACE-2, also known as angiotensin-converting enzyme 2, is an integral membrane protein and a zinc metalloprotease of the ACE family that also includes somatic and germinal ACE. It cleaves angiotensin 1 to angiotensin 1-9 and angiotensin 2 to angiotensin 1-7 as a carboxypeptidase. It may be an important regulator of heart function and have a protective role in acute lung injury. Also, it is a key SARS-CoV Spike protein receptor in vivo. Recombinant mouse ACE-2, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
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Molecular Weight
- 84.5 kDa (731aa)
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NCBI Accession
- NP_081562
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Pathways
- ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour
Target
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