CRYAB Protein (AA 1-175) (His tag)
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- Target See all CRYAB Proteins
- CRYAB (Crystallin, alpha B (CRYAB))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-175
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This CRYAB protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
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MDIAIHHPWI RRPFFPFHSP SRLFDQFFGE HLLESDLFPT STSLSPFYLR PPSFLRAPSW FDTGLSEMRL EKDRFSVNLD VKHFSPEELK VKVLGDVIEV HGKHEERQDE HGFISREFHR KYRIPADVDP LTITSSLSSD GVLTVNGPRK QVSGPERTIP ITREEKPAVT AAPKK
- Purity
- > 90% by SDS-PAGE
- Top Product
- Discover our top product CRYAB Protein
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.
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- Target
- CRYAB (Crystallin, alpha B (CRYAB))
- Alternative Name
- Crystallin alpha B/CRYAB (CRYAB Products)
- Background
- Alpha crystallins are composed of two gene products , alpha-A and alpha-B, for acidic and basic, respectively. Alpha crystallins can be induced by heat shock and are members of the small heat shock protein (sHSP also known as the HSP20). They act as molecular chaperones and hold them in in large soluble aggregates. These heterogeneous aggregates consist of 30-40 subunits, the alpha-A and alpha-B subunits have a 3:1 ratio, respectively. Two additional function of alpha-crystallins are an autokinase activity and participation in the intracellular architecture. Alpha-B is expressed widely in many tissues and organs and occurs in many neurological diseases.
- Molecular Weight
- 21.2 kDa (183aa)
- NCBI Accession
- NP_001876
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