CRYAB Protein (His tag)

Catalog No. ABIN7319198

Product Details

Target: CRYAB (Crystallin, alpha B (CRYAB))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This CRYAB protein is labelled with His tag.

Purpose: Recombinant Human CRYAB Protein (His Tag)

Sequence: Met 1-Lys175

Characteristics: Recombinant Human Crystalline alpha -B chain is produced by our E.coli expression system and the target gene encoding Met1-Lys175 is expressed with a 6His tag at the C-terminus.

Purity: > 95 % as determined by reducing SDS-PAGE.

Endotoxin Level: < 1.0 EU per μg as determined by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Target Details

Target: CRYAB (Crystallin, alpha B (CRYAB))

Alternative Name: CRYAB (CRYAB Products)

Synonyms: CMD1II Protein, CRYA2 Protein, CTPP2 Protein, CTRCT16 Protein, HSPB5 Protein, MFM2 Protein, Crya-2 Protein, Crya2 Protein, HspB5 Protein, AACRYA Protein, CRYAB Protein, cryab Protein, cryab2 Protein, wu:fe37f08 Protein, zgc:91937 Protein, crystallin alpha B Protein, crystallin, alpha B Protein, hypothetical protein Protein, crystallin, alpha B, a Protein, crystallin, alpha B, b Protein, CRYAB Protein, Cryab Protein, ZK1128.7 Protein, cryaba Protein, cryabb Protein

Background:

Background: α Crystallin B Chain (CRYAB) is a cytoplasmic protein that belongs to the small heat shock protein (HSP20) family. Alpha crystallins are composed of two gene products: alpha-A and alpha-B, for acidic and basic, respectively. Alpha crystallins can be induced by heat shock and are members of the small heat shock protein (sHSP also known as the HSP20) family. Alpha crystallins acts as molecular chaperones and hold them in in large soluble aggregates. CRYAB is expressed widely in many tissues and organs. It may contribute to the transparency and refractive index of the lens. The deficiency of CRYAB is the cause of myopathy myofibrillar type 2 (MFM2) and cataract posterior polar type 2 (CTPP2).

Synonym: Alpha-Crystallin B Chain, Alpha(B)-Crystallin, Heat Shock Protein Beta-5, HspB5, Renal Carcinoma Antigen NY-REN-27, Rosenthal Fiber Component, CRYAB, CRYA2

Molecular Weight: 21.2 kDa

UniProt: P02511