MAP2K6 Protein (AA 1-334) (His tag)
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- Target See all MAP2K6 Proteins
- MAP2K6 (Mitogen-Activated Protein Kinase Kinase 6 (MAP2K6))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-334
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Origin
- Human
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Source
- Baculovirus infected Insect Cells
- Purification tag / Conjugate
- This MAP2K6 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
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MSQSKGKKRN PGLKIPKEAF EQPQTSSTPP RDLDSKACIS IGNQNFEVKA DDLEPIMELG RGAYGVVEKM RHVPSGQIMA VKRIRATVNS QEQKRLLMDL DISMRTVDCP FTVTFYGALF REGDVWICME LMDTSLDKFY KQVIDKGQTI PEDILGKIAV SIVKALEHLH SKLSVIHRDV KPSNVLINAL GQVKMCDFGI SGYLVDSVAK TIDAGCKPYM APERINPELN QKGYSVKSDI WSLGITMIEL AILRFPYDSW GTPFQQLKQV VEEPSPQLPA DKFSAEFVDF TSQCLKKNSK ERPTYPELMQ HPFFTLHESK GTDVASFVKL ILGD
- Purity
- > 90% by SDS-PAGE
- Endotoxin Level
- < 1 EU per 1ug of protein (determined by LAL method)
- Top Product
- Discover our top product MAP2K6 Protein
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Mitogen-Activated Protein Kinase Kinase 6 (MAP2K6) (AA 1-334) protein (His tag)
custom-made MAP2K6 Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Mitogen-Activated Protein Kinase Kinase 6 (MAP2K6) (AA 1-334) protein (His tag)custom-made MAP2K6 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Mitogen-Activated Protein Kinase Kinase 6 (MAP2K6) (AA 6-334) protein (His tag)MAP2K6 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Mitogen-Activated Protein Kinase Kinase 6 (MAP2K6) (AA 1-334) protein (GST tag)MAP2K6 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Mitogen-Activated Protein Kinase Kinase 6 (MAP2K6) protein (GST tag,His tag)MAP2K6 Origin: Human Host: Baculovirus infected Insect Cells Recombinant > 80 % as determined by reducing SDS-PAGE.
Mitogen-Activated Protein Kinase Kinase 6 (MAP2K6) (Active) protein (GST tag,His tag)MAP2K6 Origin: Human Host: Baculovirus infected Insect Cells Recombinant > 88 % as determined by reducing SDS-PAGE. Active
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.
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- Target
- MAP2K6 (Mitogen-Activated Protein Kinase Kinase 6 (MAP2K6))
- Alternative Name
- MKK6 (MAP2K6 Products)
- Background
- MKK6, also known as dual specificity mitogen-activated protein kinase kinase 6, is a member of the dual specificity protein kinase family, which functions as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein phosphorylates and activates p38 MAP kinase in response to inflammatory cytokines or environmental stress. As an essential component of p38 MAP kinase mediated signal transduction pathway, this gene is involved in many cellular processes such as stress-induced cell cycle arrest, transcription activation and apoptosis. Recombinant human MKK6, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
- Molecular Weight
- 38.3 kDa (340aa) confirmed by MALDI-TOF
- NCBI Accession
- NP_002749
- Pathways
- MAPK Signaling, TLR Signaling, Activation of Innate immune Response, Regulation of Muscle Cell Differentiation, Toll-Like Receptors Cascades
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