MAP2K6 Protein (GST tag,His tag)
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- Target See all MAP2K6 Proteins
- MAP2K6 (Mitogen-Activated Protein Kinase Kinase 6 (MAP2K6))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Baculovirus infected Insect Cells
- Purification tag / Conjugate
- This MAP2K6 protein is labelled with GST tag,His tag.
- Purpose
- Recombinant Human MKK6 Protein (His & GST Tag)
- Sequence
- Met 1-Asp 334
- Characteristics
- A DNA sequence encoding the human MKK6 isoform 1 (P52564-1) (Met 1-Asp 334) was fused with the N-terminal polyhistidine-tagged GST tag at the N-terminus.
- Purity
- > 80 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product MAP2K6 Protein
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Mitogen-Activated Protein Kinase Kinase 6 (MAP2K6) (AA 1-334) (Active) protein (GST tag)
MAP2K6 Origin: Human Host: Escherichia coli (E. coli) Recombinant SDS, Func Active
Mitogen-Activated Protein Kinase Kinase 6 (MAP2K6) (Lys82Ala-Mutant) (Active) protein (GST tag)MAP2K6 Origin: Human Host: Escherichia coli (E. coli) Recombinant SDS, Func Active
Mitogen-Activated Protein Kinase Kinase 6 (MAP2K6) (Ser207Asp-Mutant), (Thr211Asp-Mutant) (Active) protein (His-GST)MAP2K6 Origin: Human Host: Insect cells (Sf9) Recombinant SDS, Func Active
Mitogen-Activated Protein Kinase Kinase 6 (MAP2K6) (AA 6-334) protein (His tag)MAP2K6 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Mitogen-Activated Protein Kinase Kinase 6 (MAP2K6) (AA 1-334) protein (GST tag)MAP2K6 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Mitogen-Activated Protein Kinase Kinase 6 (MAP2K6) (AA 231-334) protein (GST tag)MAP2K6 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Mitogen-Activated Protein Kinase Kinase 6 (MAP2K6) (Active) protein (GST tag,His tag)MAP2K6 Origin: Human Host: Baculovirus infected Insect Cells Recombinant > 88 % as determined by reducing SDS-PAGE. Active
Mitogen-Activated Protein Kinase Kinase 6 (MAP2K6) (AA 1-334) protein (Strep Tag)Crystallography grade MAP2K6 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
Mitogen-Activated Protein Kinase Kinase 6 (MAP2K6) (AA 1-334) protein (Strep Tag)Crystallography grade MAP2K6 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
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- Restrictions
- For Research Use only
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- Format
- Frozen, Liquid
- Buffer
- Supplied as sterile 20 mM Tris, 500 mM NaCl, pH 8.0
- Storage
- -20 °C
- Storage Comment
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- Target
- MAP2K6 (Mitogen-Activated Protein Kinase Kinase 6 (MAP2K6))
- Alternative Name
- MKK6 (MAP2K6 Products)
- Synonyms
- MAPKK6 Protein, MEK6 Protein, MKK6 Protein, PRKMK6 Protein, SAPKK-3 Protein, SAPKK3 Protein, Mkk6 Protein, Prkmk6 Protein, MKK3 Protein, map2k3 Protein, zMKK3 Protein, map2k6 Protein, mitogen-activated protein kinase kinase 6 Protein, mitogen-activated protein kinase kinase 6 L homeolog Protein, MAP2K6 Protein, Map2k6 Protein, map2k6 Protein, map2k6.L Protein
- Background
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Background: Dual specificity mitogen-activated protein kinase kinase 6, also known as MAP kinase kinase 6, MAPKK 6, MAPK / ERK kinase 6, SAPKK3, MAP2K6 and MKK6, is a protein which belongs to the?protein kinase superfamily, STE Ser / Thr protein kinase family and MAP kinase kinase subfamily. MAP2K6 / MKK6 contains one?protein kinase domain. Mitogen-activated protein kinases are members of a conserved cascade of kinases involved in many signal transduction pathways. They stimulate phosphorylation of transcription factors in response to extracellular signals such as growth factors, cytokines, ultraviolet light, and stress-inducing agents. MAP2K6 / MKK6 exists in a variety of alternatively spliced isoforms with distinct patterns of tissue expression. Isoform 2 of MAP2K6 / MKK6 is only expressed in skeletal muscle. Isoform 1 of MAP2K6 / MKK6 is expressed in skeletal muscle, heart, and in lesser extent in liver or pancreas.
Synonym: MAPKK6,MEK6,MKK6,PRKMK6,SAPKK-3,SAPKK3,MAP2K6
- Molecular Weight
- 65.3 kDa
- Pathways
- MAPK Signaling, TLR Signaling, Activation of Innate immune Response, Regulation of Muscle Cell Differentiation, Toll-Like Receptors Cascades
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