CRTAM Protein (AA 18-287) (Fc Tag)
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- Target See all CRTAM Proteins
- CRTAM (Cytotoxic and Regulatory T Cell Molecule (CRTAM))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 18-287
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This CRTAM protein is labelled with Fc Tag.
- Purpose
- Recombinant human CRTAM Protein with C-terminal human Fc tag
- Sequence
- CRTAM(Ser18-Gly287) hFc(Glu99-Ala330)
- Purity
- The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
- Top Product
- Discover our top product CRTAM Protein
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Cytotoxic and Regulatory T Cell Molecule (CRTAM) (AA 18-287) protein (Fc Tag)
CRTAM Origin: Cynomolgus Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Cytotoxic and Regulatory T Cell Molecule (CRTAM) (AA 18-287) protein (His tag)CRTAM Origin: Cynomolgus Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Cytotoxic and Regulatory T Cell Molecule (CRTAM) (AA 18-287) protein (His tag)CRTAM Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Cytotoxic and Regulatory T Cell Molecule (CRTAM) (AA 17-289) protein (His tag)CRTAM Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Cytotoxic and Regulatory T Cell Molecule (CRTAM) (AA 18-287) protein (His tag)CRTAM Origin: Dog Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Cytotoxic and Regulatory T Cell Molecule (CRTAM) (AA 1-393) protein (GST tag)CRTAM Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
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- Application Notes
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Extracellular Domain Proteins (ECD) can be used as:
- Immunogens for antibody drug development
- Reagents used for CAR-T positive cell monitoring
- Reagents for antibody screening and functional testing
- Reagents for antibody affinity measurement
- Comment
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The protein was made using HEK293 mammalian cell secretion expression system to ensure the close-to-native structures and post-translational modifications of the target protein.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- CRTAM (Cytotoxic and Regulatory T Cell Molecule (CRTAM))
- Alternative Name
- CRTAM (CRTAM Products)
- Background
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CD355
The CRTAM gene is upregulated in CD4 (see MIM 186940)-positive and CD8 (see CD8A, MIM 186910)-positive T cells and encodes a type I transmembrane protein with V and C1-like Ig domains (Yeh et al., 2008 [PubMed 18329370]).[supplied by OMIM, Feb 2009] - Molecular Weight
- predicted molecular mass of 56.1 kDa after removal of the signal peptide. The apparent molecular mass of CRTAM-hFc is 70-100 kDa due to glycosylation.
- UniProt
- O95727
- Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation
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