IGFBP6 Protein (AA 25-240) (His tag)

Catalog No. ABIN7678448

Recombinant IGFBP6 protein expressed in Mammalian Cells.

Quick Overview for IGFBP6 Protein (AA 25-240) (His tag) (ABIN7678448)

Target: IGFBP6 (Insulin-Like Growth Factor Binding Protein 6 (IGFBP6))

Protein Type: Recombinant

Biological Activity: Active

Origin: Human

Source: Mammalian Cells

Application: SDS-PAGE (SDS), Western Blotting (WB), Immunogen (Imm), ELISA, Activity Assay (AcA)

Purity: >90 % as determined by SDS-PAGE.

Product Details

Protein Characteristics: AA 25-240

Purification tag / Conjugate: This IGFBP6 protein is labelled with His tag.

Purpose: Recombinant Human IGFBP6 Protein, C-His (Active)

Endotoxin Level: <0.1 EU/μg of the protein by the LAL method.

Biological Activity Comment: Measured by its ability to inhibit the biological activity of IGF-I or IGF-II on human breast cancer cells (MCF-7). The ED50 for this effect is 0.025-0.15 μg/mL in the presence of 14 ng/mL recombinant human IGF-II.

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Lyophilized from a solution in PBS pH 7.4, 5 % Trehalose, 5 % Mannitol.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at -20 to -80°C for twelve months from the date of receipt.

Expiry Date: 12 months

Target Details

Target: IGFBP6 (Insulin-Like Growth Factor Binding Protein 6 (IGFBP6))

Alternative Name: Insulin-like growth factor-binding protein 6

Background: Insulin-like growth factor-binding protein 6, IBP-6, IBP6, IGFBP-6, IGF-binding protein 6, IGFBP6

UniProt: P24592

Pathways: WNT Signaling, Myometrial Relaxation and Contraction