LIFR Protein (AA 1-833) (His tag)

Catalog No. ABIN7678511

Recombinant LIFR protein expressed in Mammalian Cells.

Quick Overview for LIFR Protein (AA 1-833) (His tag) (ABIN7678511)

Target: LIFR (Leukemia Inhibitory Factor Receptor alpha (LIFR))

Protein Type: Recombinant

Biological Activity: Active

Origin: Human

Source: Mammalian Cells

Application: Western Blotting (WB), SDS-PAGE (SDS), Immunogen (Imm), ELISA, Activity Assay (AcA)

Purity: >90 % as determined by SDS-PAGE.

Product Details

Protein Characteristics: AA 1-833

Purification tag / Conjugate: This LIFR protein is labelled with His tag.

Purpose: Recombinant Human CD118/LIFR Protein, C-His (Active)

Endotoxin Level: <0.1 EU/μg of the protein by the LAL method.

Biological Activity Comment: Measured by its ability to inhibit LIF-dependent proliferation of human erythroleukemic cells (TF-1). The ED50 for this effect is typically 1-6 μg/mL in the presence of 0.3 ng/mL of rh LIF.

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Lyophilized from a solution in PBS pH 7.4, 5 % Trehalose, 5 % Mannitol.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at -20 to -80°C for twelve months from the date of receipt.

Expiry Date: 12 months

Target Details

Target: LIFR (Leukemia Inhibitory Factor Receptor alpha (LIFR))

Alternative Name: LIFR

Background: LIFR, LIF-R, CD118, LIF receptor, Leukemia inhibitory factor receptor

UniProt: P42702

Pathways: JAK-STAT Signaling, Growth Factor Binding