IL12RB2 Protein (AA 24-622) (His-Fc tag)

Catalog No. ABIN7678738

Recombinant IL12RB2 protein expressed in Mammalian Cells.

Quick Overview for IL12RB2 Protein (AA 24-622) (His-Fc tag) (ABIN7678738)

Target: IL12RB2 (Interleukin 12 Receptor, beta 2 (IL12RB2))

Protein Type: Recombinant

Biological Activity: Active

Origin: Human

Source: Mammalian Cells

Application: Western Blotting (WB), SDS-PAGE (SDS), Immunogen (Imm), ELISA, Activity Assay (AcA)

Purity: >90 % as determined by SDS-PAGE.

Product Details

Protein Characteristics: AA 24-622

Purification tag / Conjugate: This IL12RB2 protein is labelled with His-Fc tag.

Purpose: Recombinant Human IL12RB2 Protein, C-hFc-His (Active)

Endotoxin Level: <0.1 EU/μg of the protein by the LAL method.

Biological Activity Comment: Measured by its binding ability in a functional ELISA. When recombinant human IL-12 is immobilized at 0.5 μg/mL, 100 μL/well, the concentration of recombinant human IL12RB2 (ABIN7607691 and ABIN7678738) that produces 50% of the optimal binding response is 0.015-0.09 μg/mL.

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Lyophilized from a solution in PBS pH 7.4, 5 % Trehalose, 5 % Mannitol.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at -20 to -80°C for twelve months from the date of receipt.

Expiry Date: 12 months

Target Details

Target: IL12RB2 (Interleukin 12 Receptor, beta 2 (IL12RB2))

Alternative Name: IL-12R subunit beta-2

Background: IL-12R subunit beta-2, IL-12 receptor subunit beta-2, IL-12R-beta-2, Interleukin-12 receptor subunit beta-2, IL12RB2, IL-12RB2

UniProt: Q99665

Pathways: JAK-STAT Signaling