FGF23 Protein (AA 25-251) (His tag)

Catalog No. ABIN7678758

This Recombinant FGF23 protein is expressed in Mammalian Cells.

Quick Overview for FGF23 Protein (AA 25-251) (His tag) (ABIN7678758)

Target: FGF23 (Fibroblast Growth Factor 23 (FGF23))

Protein Type: Recombinant

Biological Activity: Active

Origin: Human

Source: Mammalian Cells

Application: SDS-PAGE (SDS), Western Blotting (WB), Immunogen (Imm), ELISA, Activity Assay (AcA)

Purity: >90 % as determined by SDS-PAGE.

Product Details

Protein Characteristics: AA 25-251

Purification tag / Conjugate: This FGF23 protein is labelled with His tag.

Purpose: Recombinant Human FGF23 Protein, C-His (Active)

Endotoxin Level: <0.1 EU/μg of the protein by the LAL method.

Biological Activity Comment: Measured in a cell proliferation assay using mouse pro-B cells (BaF3) transfected with human FGF RIIIc. The ED50 for this effect is 0.1-0.4 μg/mL in the presence of recombinant Mouse Klotho and heparin.

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Lyophilized from a solution in PBS pH 7.4, 5 % Trehalose, 5 % Mannitol.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at -20 to -80°C for twelve months from the date of receipt.

Expiry Date: 12 months

Target Details

Target: FGF23 (Fibroblast Growth Factor 23 (FGF23))

Alternative Name: Phosphatonin

Background: Phosphatonin, FGF-23, HYPF, FGF23, Fibroblast growth factor 23, Tumor-derived hypophosphatemia-inducing factor

UniProt: Q9GZV9

Pathways: RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Negative Regulation of Hormone Secretion