Cofilin 2 Protein (CFL2) (His tag)
Quick Overview for Cofilin 2 Protein (CFL2) (His tag) (ABIN7668552)
Target
See all Cofilin 2 (CFL2) ProteinsProtein Type
Origin
Source
Purity
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Purification tag / Conjugate
- This Cofilin 2 protein is labelled with His tag.
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Purpose
- Recombinant Human CFL2/cofilin 2/ADF Protein (His Tag)
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Sequence
- Ala 2-Leu 166
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Purification
- > 98 % as determined by reducing SDS-PAGE.
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Sterility
- 0.2 μm filtered
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Biological Activity Comment
- Not validated for activity
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Cofilin 2 (CFL2) (AA 1-166) protein (GST tag)
CFL2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Cofilin 2 (CFL2) (AA 1-166) protein (His tag)CFL2 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
Cofilin 2 (CFL2) (AA 1-166) protein (His-IF2DI Tag)CFL2 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Cofilin 2 (CFL2) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)CFL2 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Cofilin 2 (CFL2) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)CFL2 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
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Lyophilized from sterile PBS, pH 7.5
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization. -
Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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Expiry Date
- 12 months
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- Cofilin 2 (CFL2)
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Alternative Name
- CFL2
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Background
- NEM7,Cofilin 2 (muscle), also known as CFL2, is a member of cofilin family of the actin-binding protein superfamily. Cofilin2 shows significant homology to the other two members: cofilin 1 and DSTN, through its entire sequence, and contains residues conserved among the cofilin family that are responsible for actin-binding. Cofilin 2 (CFL2) is an important regulator of striated myocyte function. Purified cofilin 2 depolymerized actin filaments in a dose- and pH -dependent manner and reduced the apparent viscosity of an actin solution, although they did not co-sediment with actin filaments at all. Cofilin2 is not expressed in vegetative cells, but is transiently induced during the aggregation stage of development, whereas cofilin 1 was predominantly expressed in vegetative cells.
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Molecular Weight
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Calculated MW: 20.4 kDa
Observed MW: 21 kDa
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Gene ID
- 1073
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UniProt
- Q9Y281
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Pathways
- Caspase Cascade in Apoptosis
Target
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