Cofilin 2 Protein (CFL2) (AA 1-166) (His tag)
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- Target See all Cofilin 2 (CFL2) Proteins
- Cofilin 2 (CFL2)
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-166
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This Cofilin 2 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- CFL2, 1-166aa, Human, His tag, E.coli
- Purity
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product CFL2 Protein
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 2mM DTT, 10% glycerol, 50mM Nacl
- Storage
- 4 °C
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- Target
- Cofilin 2 (CFL2)
- Alternative Name
- CFL2 (CFL2 Products)
- Synonyms
- NEM7 Protein, CFL2 Protein, zgc:77288 Protein, cf12 Protein, cofilin 2 Protein, cofilin 2 (non-muscle) Protein, cofilin 2 (muscle) Protein, cofilin 2, muscle Protein, cofilin-2 Protein, CFL2 Protein, cfl2 Protein, Cfl2 Protein, cf12 Protein, LOC100359205 Protein
- Background
- CFL2 protein belongs to the actin-binding proteins ADF family that contains 1 ADF-H domain. Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. Defects in CFL2 are the cause of nemaline myopathy type 7 (NEM7). Recombinant human CFL2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Cofilin-2, NEM7. NCBI no.: NP_068733
- Molecular Weight
- 20.9kDa (186a), confirmed by MALDI-TOF
- Pathways
- Caspase Cascade in Apoptosis
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