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Hepcidin Protein (AA 59-83) (His-TRX)

This Recombinant Hepcidin protein is produced in Escherichia coli (E. coli).
Catalog No. ABIN7668892
$1,902.46
Plus shipping costs $50.00
500 μg
Shipping to: United States
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Quick Overview for Hepcidin Protein (AA 59-83) (His-TRX) (ABIN7668892)

Target

See all Hepcidin (HAMP) Proteins
Hepcidin (HAMP) (Hepcidin Antimicrobial Peptide (HAMP))

Protein Type

Recombinant

Origin

  • 12
  • 5
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
Mouse

Source

  • 19
  • 3
  • 3
  • 1
Escherichia coli (E. coli)

Application

Immunogen (Imm)

Purity

> 95 % as determined by reducing SDS-PAGE.
  • Protein Characteristics

    AA 59-83

    Purification tag / Conjugate

    This Hepcidin protein is labelled with His-TRX.

    Purpose

    Recombinant Mouse Hepcidin/Hepc Protein (TRX,His Tag)

    Sequence

    Asp59-Thr83

    Sterility

    0.2 μm filtered

    Endotoxin Level

    < 10 EU/mg of the protein as determined by the LAL method

    Biological Activity Comment

    Not validated for activity
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  • Application Notes

    Optimal working dilution should be determined by the investigator.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

    Buffer

    Lyophilized from a 0.2 μm filtered solution in PBS with 5 % Trehalose and 5 % Mannitol.

    Storage

    4 °C,-20 °C,-80 °C

    Storage Comment

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

    Expiry Date

    12 months
  • Target

    Hepcidin (HAMP) (Hepcidin Antimicrobial Peptide (HAMP))

    Alternative Name

    Hepcidin,Hepc

    Background

    HEPC_MOUSE,Hamp,Hamp1,Hepc,Hepc1,Hepcidin,Liver-produced hormone that constitutes the main circulating regulator of iron absorption and distribution across tissues. Acts by promoting endocytosis and degradation of ferroportin, leading to the retention of iron in iron-exporting cells and decreased flow of iron into plasma. Controls the major flows of iron into plasma: absorption of dietary iron in the intestine, recycling of iron by macrophages, which phagocytose old erythrocytes and other cells, and mobilization of stored iron from hepatocytes.

    Molecular Weight

    Calculated MW: 22.6 kDa

    Observed MW: 25 kDa

    Gene ID

    84506

    UniProt

    Q9EQ21

    Pathways

    Hormone Activity, Transition Metal Ion Homeostasis
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