IL28B Protein (His tag)

Catalog No. ABIN7669104

Recombinant IL28B protein expressed in Escherichia coli (E. coli).

Quick Overview for IL28B Protein (His tag) (ABIN7669104)

Target: IL28B (Interleukin 28B (Interferon, lambda 3) (IL28B))

Protein Type: Recombinant

Biological Activity: Inactive

Origin: Human

Source: Escherichia coli (E. coli)

Purity: > 95 %

Product Details

Purification tag / Conjugate: This IL28B protein is labelled with His tag.

Purpose: Recombinant Human IL-28B/IFN-lambda-3 protein (His tag)

Sequence: Val 22-Val 196

Sterility: 0.2 μm filtered

Endotoxin Level: < 10 EU/mg of the protein as determined by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

Buffer: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % -8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Expiry Date: 12 months

Target Details

Target: IL28B (Interleukin 28B (Interferon, lambda 3) (IL28B))

Alternative Name: IL-28B,IFN-lambda-3

Background: Interleukin-28B, also known as Cytokine Zcyto22, Interferon lambda-3, Interferon lambda-4, IFNL3, IFNL4, ZCYTO22 and IL28B, is a secreted cytokine which belongs to the IL-28/IL-29 family. IL-28 has also been shown to play a role in the adaptive immune response. IL28B has immunomodulatory activity and up-regulates MHC class I antigen expression. IL28B displays potent antiviral activity and antitumor activity. In addition, IL28B is a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IL28RA. The ligand/receptor complex seems to signal through the Jak-STAT pathway.,Cytokine Zcyto,ZCYTO,IFNL3,IFN-lambda-3,IFN-lambda-4,IL-28B,IL-28C,IL28B,IL28C,Cytokine Zcyto22,IFNL4,IFN-lambda 3,interferon lambda 3,Interferon Lambda-3,Interferon Lambda-4,Interleukin-28B,Interleukin-28C,ZCYTO22

Molecular Weight:

calculated_mw: 19.1 kDa

observed_mw: 25 kDa

UniProt: Q8IZI9