Renin Protein (REN) (His tag)
Quick Overview for Renin Protein (REN) (His tag) (ABIN7669527)
Target
See all Renin (REN) ProteinsProtein Type
Biological Activity
Origin
Source
Purity
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Purification tag / Conjugate
- This Renin protein is labelled with His tag.
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Purpose
- Recombinant Human Renin protein (His tag)
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Sequence
- Leu 67-406Arg
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Purification
- > 95 % as determined by reducing SDS-PAGE.
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Sterility
- 0.2 μm filtered
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Endotoxin Level
- < 10 EU/mg of the protein as determined by the LAL method.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.
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Buffer
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % -8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization. -
Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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Expiry Date
- 12 months
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- Renin (REN)
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Alternative Name
- Renin
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Background
- Renin is a highly specific endopeptidase, whose only known function is to generate angiotensin I from angiotensinogen in the plasma, initiating a cascade of reactions that produce an elevation of blood pressure and increased sodium retention by the kidney.,Angiotensin forming enzyme,HNFJ2,REN
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Molecular Weight
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calculated_mw: 37.3 kDa
observed_mw: 40 kDa
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UniProt
- P00797
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Pathways
- ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour
Target
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