Thyroperoxidase Protein (His tag)
Quick Overview for Thyroperoxidase Protein (His tag) (ABIN7669835)
Target
See all Thyroperoxidase (TPO) ProteinsProtein Type
Origin
Source
Purity
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Purification tag / Conjugate
- This Thyroperoxidase protein is labelled with His tag.
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Purpose
- Recombinant Human TPO protein(His Tag)
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Sequence
- Ser 22-Leu 195
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Purification
- > 95 % as determined by reducing SDS-PAGE.
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Sterility
- 0.2 μm filtered
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Endotoxin Level
- < 0.01 EU per μg of the protein as determined by the LAL method.
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Biological Activity Comment
- Not validated for activity
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization. -
Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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Expiry Date
- 12 months
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- Thyroperoxidase (TPO) (Thyroid Peroxidase (TPO))
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Alternative Name
- TPO
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Background
- MGDF,Megakaryocyte colony-stimulating factor,c-MPL Ligand,Thrombopoietin (TPO) is a glycoprotein hormone which belongs to the EPO/TPO family. It produced by the liver and kidney which regulates the production of platelets. TPO stimulates the production and differentiation of megakaryocytes, the bone marrow cells that bud off large numbers of platelets. Lineage-specific cytokine affects the proliferation and maturation of megakaryocytes from their committed progenitor cells. It acts at a late stage of megakaryocyte development. It may be the major physiological regulator of circulating platelets.
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Molecular Weight
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Calculated MW: 19.6 kDa
Observed MW: 20 kDa
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Gene ID
- 7066
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UniProt
- P40225
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Pathways
- Thyroid Hormone Synthesis
Target
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