FGF2 Protein

Catalog No. ABIN7680469

This Recombinant FGF2 protein is expressed in Rice (Oryza sativa).

Quick Overview for FGF2 Protein (ABIN7680469)

Target: FGF2 (Fibroblast Growth Factor 2 (Basic) (FGF2))

Protein Type: Recombinant

Biological Activity: Active

Origin: Human

Source: Rice (Oryza sativa)

Application: Cell Culture (CC)

Purity: More than 95 % as determined by SDS-PAGE. 

Grade: Animal-Free

Product Details

Purpose: OsrhbFGF - Recombinant human basic fibroblast growth factor

Characteristics: The recombinant Osrh products are expressed in the rice endosperm platform, which is animal-free and has high purity. It avoids the risk of contamination from human or animal-derived viruses and mycoplasma. The rice endosperm platform has high scalability.This product arrives as White lyophilized powder 

Endotoxin Level: Less than 1 EU/μg

Biological Activity Comment: The ED50 is ≤1ng/ml determined by a cell proliferation assay using Balb/c 3T3, corresponding to a specific activity of ≥1x10^6 Units/mg.

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: It is recommended to reconstitute the lyophilized OsrhbFGF in sterile water.

Buffer: It is lyophilized with trehalose as the stabilizer.

Handling Advice: Use as soon as possible after opening. Avoid freeze-thaw cycles

Storage: -20 °C

Storage Comment: Stored at temperatures -20°C for at least 36 months.  Use as soon as possible after opening. Please avoid freeze-thaw cycles.

Expiry Date: 36 months

Target Details

Target: FGF2 (Fibroblast Growth Factor 2 (Basic) (FGF2))

Alternative Name: basic fibroblast growth factor

Background: Human basic fibroblast growth factor, also known as bFGF, FGF2 or FGF-β, is a member of the fibroblast growth factor family. It is a single-chain polypeptide growth factor that plays a significant role in the process of promoting cell proliferation, inhibiting cell apoptosis, expediting wound healing and inducing angiogenesis. It is also a very potent inducer of DNA synthesis in a variety of cell types from mesoderm and neuroectoderm lineages.

Pathways: RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, C21-Steroid Hormone Metabolic Process, Inositol Metabolic Process, Glycosaminoglycan Metabolic Process, Protein targeting to Nucleus, S100 Proteins