FGF7 Protein

Catalog No. ABIN7680481

Recombinant FGF7 protein expressed in Rice (Oryza sativa).

Quick Overview for FGF7 Protein (ABIN7680481)

Target: FGF7 (Fibroblast Growth Factor 7 (FGF7))

Protein Type: Recombinant

Biological Activity: Active

Origin: Human

Source: Rice (Oryza sativa)

Application: Cell Culture (CC)

Purity: More than 95 % as determined by SDS-PAGE. 

Grade: Animal-Free

Product Details

Purpose: OsrhKGF - Recombinant Human Keratinocyte Growth Factor

Characteristics: The recombinant Osrh products are expressed in the rice endosperm platform, which is animal-free and has high purity. It avoids the risk of contamination from human or animal-derived viruses and mycoplasma. The rice endosperm platform has high scalability.This product arrives as White lyophilized powder

Endotoxin Level: Less than 0.1 EU/mg

Biological Activity Comment: The ED50 is ≤1ng/ml determined by a cell proliferation assay using MCF-7, corresponding to a specific activity of ≥1x10^6 Units/mg.

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

OsrhKGF, expressed in the rice endosperm platform and purified by chromatography, is animal component free and has high biological activity. The rice endosperm platform makes the manufacture capability at hundreds of gram scales to meet your bulk bioprocessing needs.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: It is recommended to reconstitute the lyophilized OsrhKGF in sterile water.

Buffer: It is lyophilized with trehalose and histidine as the stabilizers.

Handling Advice: Use as soon as possible after opening. Avoid freeze-thaw cycles

Storage: -20 °C

Storage Comment: Stored at temperatures -20°C for at least 36 months. Use as soon as possible after opening. Please avoid freeze-thaw cycles.

Expiry Date: 36 months

Target Details

Target: FGF7 (Fibroblast Growth Factor 7 (FGF7))

Alternative Name: Keratinocyte Growth Factor

Background: Keratinocyte growth factor (KGF) , also known as FGF-7, is a member of FGF family. It is a cytokine discovered in the culture supernatant of embryonic lung fibroblasts. KGF, an effective epithelial cell-specific growth factor, is secreted by mesenchymal cells and its receptor is distributed in epithelial cells. Its mitotic activity is mainly manifested in keratinocytes, which can specifically stimulate the proliferation, migration and differentiation of epithelial cells. It also closely relate to organ development, wound healing, tumorigenesis and immune reconstruction etc.

Pathways: RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway