Thyroperoxidase Protein
Quick Overview for Thyroperoxidase Protein (ABIN7849670)
Target
See all Thyroperoxidase (TPO) ProteinsProtein Type
Origin
Source
Application
Purity
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Purpose
- Recombinant Human Thyroid peroxidase, TPOProtein
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Thyroid Peroxidase (TPO) (AA 32-834) (Active) protein (His tag)
TPO Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Thyroid Peroxidase (TPO) (AA 19-846) (Active) protein (His tag)TPO Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Thyroid Peroxidase (TPO) (AA 672-779) protein (GST tag)TPO Origin: Human Host: Wheat germ Recombinant AP, AA, ELISA, WB
Thyroid Peroxidase (TPO) (AA 1-933) protein (GST tag)TPO Origin: Human Host: Wheat germ Recombinant AP, AA, ELISA, WB
Thyroid Peroxidase (TPO) protein (His tag)TPO Origin: Human Host: HEK-293 Cells Recombinant Greater than 95 % as determined by reducing SDS-PAGE. AM, ADA, IA, ScA
Thyroid Peroxidase (TPO) (Active) protein (His tag)GMP Grade TPO Origin: Human Host: Escherichia coli (E. coli) Recombinant >95 % WB Active
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- 20 mM Tris-HCl ( pH 8.0).
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Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Ship at 4°C. Upon receipt, aliquot and store at -20°C or -80°C for long term. Avoid repeated freeze and thaw cycles.
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- Thyroperoxidase (TPO) (Thyroid Peroxidase (TPO))
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Alternative Name
- TPO
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Background
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Synonyms: Thyroid peroxidase, TPO, thyroperoxidase, iodide peroxidase
Description: Recombinant human TPO protein.
Background: Thyroid peroxidase, also called thyroperoxidase (TPO) or iodide peroxidase, is an enzyme expressed mainly in the thyroid where it is secreted into colloid. In humans, thyroperoxidase is encoded by the TPO gene. Thyroid peroxidase (TPO) deficiency, caused by biallelic TPO mutations, is a well-established genetic form of congenital hypothyroidism (CH). TPO mutations with residual activity are associated with mild TPO deficiency, which is clinically characterized by marked goiter, mild TSH elevation, high serum T3to T4Molar ratio, and high serum thyroglobulin levels.
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Pathways
- Thyroid Hormone Synthesis
Target
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