Pro BDNF Protein

Catalog No. ABIN7849685

This Recombinant Pro BDNF protein is expressed in Escherichia coli (E. coli).

Quick Overview for Pro BDNF Protein (ABIN7849685)

Target: Pro BDNF (proBDNF) (Pro-Brain-Derived Neurotrophic Factor (proBDNF))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Application: SDS-PAGE (SDS)

Purity: >95 % by SDS-PAGE

Product Details

Purpose: Recombinant Human pro-BDNF Protein

Endotoxin Level: <1 EU/μg by LAL test

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid,Supplied as a 0.2 μm filtered solution of 20 mM Tris-HCl,10 % Trehalose,10 % Glycerol,200 mM NaCl,1 mM EDTA,0.05 % Tween80, pH 7.8.

Preservative: Other preservative

Storage: 4 °C

Storage Comment: Ship at 4°C.Upon receipt, aliquot and store at -70°C for 6 months. Avoid repeated freeze and thaw cycles.

Target Details

Target: Pro BDNF (proBDNF) (Pro-Brain-Derived Neurotrophic Factor (proBDNF))

Alternative Name: pro-BDNF

Background:

Synonyms: ANON2, BULN2, BDNF, brain-derived neurotrophic factor, brain derived neurotrophic factor

Description: Recombinant human pro-BDNF is produced by the E.coli system, with the target gene encoding Ala19- Arg247(R125A,R127A,R128A) expressed.

Background: Brain-derived neurotrophic factors (Bdnf), or abrineurin,is a proteinthat, in humans, is encoded by the BDNF gene.BDNF is a member of the neurotrophin family of growth factors, which are related to the canonical nerve growth factor (NGF), a family which also includes NT-3 and NT-4/NT-5. Neurotrophic factors are found in the brain and the periphery. BDNF was first isolated from a pig brain in 1982 by Yves-Alain Barde and Hans Thoenen.BDNF activates the TrkB tyrosine kinase receptor.

UniProt: P23560