GDNF Protein
Quick Overview for GDNF Protein (ABIN7849696)
Target
See all GDNF ProteinsProtein Type
Origin
Source
Application
Purity
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Purpose
- Recombinant Human GDNF Protein
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Sterility
- 0.2 μm filtered
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Endotoxin Level
- <1 EU/μg by LAL test
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Glial Cell Line Derived Neurotrophic Factor (GDNF) protein (Biotin)
GDNF Origin: Human Host: Escherichia coli (E. coli) Recombinant WB, FACS, LCI, IF, FM
Glial Cell Line Derived Neurotrophic Factor (GDNF) (AA 1-211) protein (GST tag)GDNF Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Glial Cell Line Derived Neurotrophic Factor (GDNF) (AA 78-211) protein (Fc Tag)GDNF Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. AM, ADA, IA, ScA
Glial Cell Line Derived Neurotrophic Factor (GDNF) (AA 78-211) protein (His-IF2DI Tag)GDNF Origin: Rat Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Glial Cell Line Derived Neurotrophic Factor (GDNF) (AA 78-211) protein (His-IF2DI Tag)GDNF Origin: Mouse Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Glial Cell Line Derived Neurotrophic Factor (GDNF) proteinGDNF Origin: Human Host: Escherichia coli (E. coli) Recombinant 98,00% SDS
Glial Cell Line Derived Neurotrophic Factor (GDNF) proteinGDNF Origin: Human Host: Escherichia coli (E. coli) Recombinant 98,00% SDS
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Dissolve the lyophilized protein in distilled water(It is not recommended to reconstitute to a concentration<100 μg/mL.)
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Buffer
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.
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Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Ship at 4°C.Upon receipt, aliquot and store at -20°C or -80°C for long term. Avoid repeated freeze and thaw cycles.
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- GDNF (Glial Cell Line Derived Neurotrophic Factor (GDNF))
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Alternative Name
- GDNF
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Background
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Synonyms: GDNF, ATF1, ATF2, glial cell derived neurotrophic factor, HFB1-HSCR3, ATF
Description: Recombinant human GDNF is produced by the E.coli system, with the target gene encoding Ser78-Ile211 expressed.
Background: Glial cell line-derived neurotrophic factor (GDNF) is a protein that, in humans, is encoded by the GDNF gene.GDNF is a small protein that potently promotes the survival of many types of neurons.It signals through GFRα receptors, particularly GFRα1. It is also responsible for the determination of spermatogonia into primary spermatocytes, i.e. it is received by RET proto-oncogene (RET) and by forming gradient with SCF it divides the spermatogonia into two cells. As the result there is retention of spermatogonia and formation of spermatocyte.
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UniProt
- P39905
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Pathways
- RTK Signaling, Synaptic Membrane, Tube Formation, Autophagy, Smooth Muscle Cell Migration
Target
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