IL-18 Protein
Quick Overview for IL-18 Protein (ABIN7849705)
Target
See all IL-18 (IL18) ProteinsProtein Type
Origin
Source
Application
Purity
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Purpose
- Recombinant Human IL-18 Protein
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Sterility
- 0.2 μm filtered
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Endotoxin Level
- <0.01 EU/μg by LAL test
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Interleukin 18 (IL18) (AA 37-193) (Active) protein (Biotin)
IL18 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by Bis-Tris PAGE,> 90 % as determined by HPLC Active
Interleukin 18 (IL18) (AA 1-193) protein (GST tag)IL18 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Interleukin 18 (IL18) (AA 36-192) proteinIL18 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
Interleukin 18 (IL18) protein (His tag)IL18 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by SDS-PAGE
Interleukin 18 (IL18) protein (GST tag)IL18 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 85 % as determined by reducing SDS-PAGE.
Interleukin 18 (IL18) (AA 37-193) protein (Fc Tag)IL18 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. AM, ADA, IA, ScA
Interleukin 18 (IL18) (AA 37-193) protein (mFc Tag)IL18 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. AM, ADA, IA, ScA
Interleukin 18 (IL18) (AA 36-192) protein (His tag)IL18 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
Interleukin 18 (IL18) (AA 37-193) protein (His-IF2DI Tag)IL18 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Dissolve the lyophilized protein in distilled water(It is not recommended to reconstitute to a concentration<100 μg/mL.)
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Buffer
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl,5 % Sucrose,0.1 % Tween80, pH 7.4.
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Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Ship at 4°C.Upon receipt, aliquot and store at -20°C or -80°C for long term. Avoid repeated freeze and thaw cycles.
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- IL-18 (IL18) (Interleukin 18 (IL18))
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Alternative Name
- IL-18
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Background
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Synonyms: IL18, IGIF, IL-18, IL-1g, IL1F4, interleukin 18
Description: Recombinant human IL-18 is produced by the E.coli system, with the target gene encoding Tyr37-Asp193 expressed.
Background: Interleukin-18 (IL-18), also known as interferon-gamma inducing factor is a protein which in humans is encoded by the IL18 gene.[The protein encoded by this gene is a proinflammatory cytokine. Many cell types, both hematopoietic cells and non-hematopoietic cells, have the potential to produce IL-18. It was first described in 1989 as a factor that induced interferon-γ (IFN-γ) production in mouse spleen cells.Originally, IL-18 production was recognized in Kupffer cells, and liver-resident macrophages. However, IL-18 is constitutively expressed in non-hematopoietic cells, such as intestinal epithelial cells, keratinocytes, and endothelial cells.IL-18 can modulate both innate and adaptive immunity and its dysregulation can cause autoimmune or inflammatory diseases.
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UniProt
- Q14116
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Pathways
- Cellular Response to Molecule of Bacterial Origin, Activated T Cell Proliferation, Cancer Immune Checkpoints, Inflammasome
Target
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