PDCD5 Protein

Catalog No. ABIN7849709

This Recombinant PDCD5 protein is expressed in Escherichia coli (E. coli).

Quick Overview for PDCD5 Protein (ABIN7849709)

Target: PDCD5 (Programmed Cell Death 5 (PDCD5))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Application: SDS-PAGE (SDS)

Purity: >95 % by SDS-PAGE

Product Details

Purpose: Recombinant Human PDCD5 Protein

Sterility: 0.2 μm filtered

Endotoxin Level: <1 EU/μg by LAL test

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Dissolve the lyophilized protein in distilled water(It is not recommended to reconstitute to a concentration<100 μg/mL.)

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM Tris-HCl, 5 % Sucrose, 5 % Mannitol, 50 mM NaCl, 0.05 % Tween 80, pH 8.4.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Ship at 4°C.Upon receipt, aliquot and store at -20°C or -80°C for long term. Avoid repeated freeze and thaw cycles.

Target Details

Target: PDCD5 (Programmed Cell Death 5 (PDCD5))

Alternative Name: PDCD5

Background:

Synonyms: PDCD5,programmed cell death 5,TFAR19

Description: Recombinant human PDCD5 is produced by the E.coli system, with the target gene encoding Met1-Tyr125 expressedwith 6x His-tag at the C-terminus.

Background: Programmed cell death protein 5 is a protein, originally identified as an apoptosis-accelerating protein,that in humans is encoded by the PDCD5 gene.This gene encodes a protein expressed in tumor cells during apoptosis independent of the apoptosis-inducing stimuli. Prior to apoptosis induction, this gene product is distributed in both the nucleus and cytoplasm.Once apoptosis is induced, the level of this protein increases and by relocation from the cytoplasm, it accumulates in the nucleus. Although its exact function is not defined, this protein is thought to play an early and universal role in apoptosis.

UniProt: O14737