GM-CSF Protein
Quick Overview for GM-CSF Protein (ABIN7849712)
Target
See all GM-CSF (CSF2) ProteinsProtein Type
Origin
Source
Application
Purity
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Purpose
- Recombinant Mouse GM-CSF Protein
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Sterility
- 0.2 μm filtered
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Endotoxin Level
- <0.01 EU/μg by LAL test
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Dissolve the lyophilized protein in distilled water(It is not recommended to reconstitute to a concentration<100 μg/mL.)
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Buffer
- Lyophilized from a 0.2 μm filtered solution of 20 mM Tris-HCl,1 mM EDTA,4 % Mannitol, pH 8.0.
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Preservative
- Other preservative
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Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Ship at 4°C.Upon receipt, aliquot and store at -20°C or -80°C for long term. Avoid repeated freeze and thaw cycles.
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- GM-CSF (CSF2) (Colony Stimulating Factor 2 (Granulocyte-Macrophage) (CSF2))
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Alternative Name
- GM-CSF
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Background
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Synonyms: CSF2, GMCSF, colony stimulating factor 2, CSF
Description: Recombinant mouse GM-CSF is produced by the E.coli system, with the target gene encoding Ala18-Lys141 expressed.
Background: Granulocyte-macrophagecolony-stimulating factor (GM-CSF), also known as colony-stimulating factor 2 (CSF2), is a monomeric glycoprotein secreted by macrophages, T cells, mast cells, natural killer cells, endothelial cells and fibroblasts that functions as a cytokine. The pharmaceutical analogs of naturally occurring GM-CSF are called sargramostim and molgramostim.Unlike granulocyte colony-stimulating factor, which specifically promotes neutrophil proliferation and maturation, GM-CSF affects more cell types, especially macrophages and eosinophils.
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UniProt
- P01587
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Pathways
- JAK-STAT Signaling, Cellular Response to Molecule of Bacterial Origin
Target
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