Interferon gamma Protein (IFNG)
Quick Overview for Interferon gamma Protein (IFNG) (ABIN7849743)
Target
See all Interferon gamma (IFNG) ProteinsProtein Type
Origin
Source
Application
Purity
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Purpose
- Recombinant Human IFN gamma,IFNgamma Protein
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Tris-HCl, pH 7.4±0.2.
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Storage
- 4 °C,-20 °C
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Storage Comment
- Ship at 4°C. Upon receipt, aliquot and store at -20°C or for long term. Avoid repeated freeze and thaw cycles.
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- Interferon gamma (IFNG)
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Alternative Name
- IFNgamma
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Background
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Synonyms: Interferon gamma, IFNG, IFN-gamma, Immune interferon, IFN gamma, IFNr.
Description: Recombinant human IFN gamma protein.
Background: Interferon-gamma (IFN-γ), early in its history was known as immune interferon, was recognized in 1970. It dimerized soluble cytokine and is the only member of the type II class of interferons. The IFN-γ monomer consists of a core of six α-helices and an extended unfolded sequence in the C-terminal region. It is produced predominantly by natural killer (NK) and natural killer T (NKT) cells. It is critical for innate and adaptive immunity against viral and intracellular bacterial infections and for tumor control. Interferon-γ 1b is used to treat chronic granulomatous disease and osteopetrosis.
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Pathways
- Interferon-gamma Pathway, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus, Autophagy
Target
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