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M-CSF/CSF1 Protein

Name: M-CSF/CSF1 Protein
SKU: ABIN7866446
Availability: InStock

Recombinant M-CSF/CSF1 protein expressed in Escherichia coli (E. coli).

Catalog No. ABIN7866446

$850.01

Plus shipping costs $50.00

50 μg

Shipping to: United States

Delivery in 6 to 8 Business Days

Quick Overview for M-CSF/CSF1 Protein (ABIN7866446)

Target

See all M-CSF/CSF1 (CSF1) Proteins

M-CSF/CSF1 (CSF1) (Colony Stimulating Factor 1 (Macrophage) (CSF1))

Protein Type

Recombinant

Biological Activity

Active

Origin

Human

Source

Escherichia coli (E. coli)

Purity

> 95 % by SDS-PAGE

Discover our top product CSF1 Protein

Purpose

Recombinant Human M-CSF Protein

Sequence

MEEVSEYCSH MIGSGHLQSL QRLIDSQMET SCQITFEFVD QEQLKDPVCY LKKAFLLVQD IMEDTMRFRD NTPNAIAIVQ LQELSLRLKS CFTKDYEEHD KACVRTFYET PLQLLEKVKN VFNETKNLLD KDWNIFSKNC NNSFAECSSQ GHERQSEGS

Specificity

Chromosomal location:1p21-p13

Characteristics

Length (aa):159

Endotoxin Level

< 0.1 ng/μg of protein (< 1EU/μg)
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Colony Stimulating Factor 1 (Macrophage) (CSF1) (AA 33-190) (Active) protein
CSF1 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active

Colony Stimulating Factor 1 (Macrophage) (CSF1) (AA 33-255) protein (Fc Tag)
CSF1 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. ScA, IA, ADA, AM

Colony Stimulating Factor 1 (Macrophage) (CSF1) (AA 33-190) (Active) protein (His-Avi Tag)
CSF1 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active

Colony Stimulating Factor 1 (Macrophage) (CSF1) (AA 33-255) protein (His tag)
CSF1 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. ScA, IA, ADA, AM

Colony Stimulating Factor 1 (Macrophage) (CSF1) (AA 33-255) (Active) protein (His tag)
CSF1 Origin: Cynomolgus Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE Active

Colony Stimulating Factor 1 (Macrophage) (CSF1) (AA 33-190) (Active) protein (Biotin,His-Avi Tag)
CSF1 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active

Colony Stimulating Factor 1 (Macrophage) (CSF1) (AA 33-190), (Isoform 3) (Active) protein
CSF1 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % as analyzed by non-reducing SDS-PAGE. Active

Colony Stimulating Factor 1 (Macrophage) (CSF1) (Active) protein
CSF1 Origin: Mouse Host: Human Cells Recombinant > 95 % as determined by SDS-PAGE Active

Colony Stimulating Factor 1 (Macrophage) (CSF1) (AA 33-255) protein (mFc Tag)
CSF1 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. ScA, IA, ADA, AM

Colony Stimulating Factor 1 (Macrophage) (CSF1) (AA 33-187) (Active) protein
CSF1 Origin: Mouse Host: CHO Cells Recombinant > 95 % as analyzed by SDS-PAGE and HPLC. Active

Application Notes

The biological activity was determined by the dose-dependent induction of proliferation in NFS60 cells (Murine myeloid Leukemia cell line).

Restrictions

For Research Use only
Format

Lyophilized

Reconstitution

water

Buffer

PBS
Target

M-CSF/CSF1 (CSF1) (Colony Stimulating Factor 1 (Macrophage) (CSF1))

Alternative Name

M-CSF

Background

Synonyms: CSF1, MCSF, CSF-1
Description: Granulocyte/Macrophage Colony-Stimulating Factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. CSF-1 induces cells of the monocyte/macrophage lineage. It plays a role in immunological defenses, bone metabolism, lipoproteins clearance, fertility and pregnancy. Macrophage Colony Stimulating Factor Human Recombinant produced in E. coli is a disulfide linked homodimer, non-glycosylated, polypeptide chain containing 2 x 159 amino acids and having a total molecular mass of 36.8 KD. M-CSF is purified by proprietary chromatographic techniques.

Molecular Weight

36.8 kDa

Gene ID

1435

NCBI Accession

NM_000757, NP_000748

UniProt

P09603

Pathways

RTK Signaling