FLT3LG Protein
Quick Overview for FLT3LG Protein (ABIN7866466)
Target
See all FLT3LG ProteinsProtein Type
Biological Activity
Origin
Source
Purity
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Purpose
- Recombinant Human Flt-3 Ligand Protein
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Sequence
- TQDCSFQHSP ISSDFAVKIR ELSDYLLQDY PVTVASNLQD EELCGGLWRL VLAQRWMERL KTVAGSKMQG LLERVNTEIH FVTKCAFQPP PSCLRFVQTN ISRLLQETSE QLVALKPWIT RQNFSRCLEL QCQPDSSTLP PPWSPRPLEA TAPTA
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Specificity
- Chromosomal location:19q13.3
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Characteristics
- Length (aa):155
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Endotoxin Level
- < 0.1 ng/μg of protein (< 1EU/μg)
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Fms-Related tyrosine Kinase 3 Ligand (FLT3LG) (AA 27-185) (Active) protein (hFc Tag)
FLT3LG Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Fms-Related tyrosine Kinase 3 Ligand (FLT3LG) (AA 27-185) (Active) protein (His tag)FLT3LG Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Fms-Related tyrosine Kinase 3 Ligand (FLT3LG) (AA 27-184) protein (His tag,mFc Tag)FLT3LG Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. AM, ADA, IA, ScA
Fms-Related tyrosine Kinase 3 Ligand (FLT3LG) (AA 27-189) (Active) protein (hFc Tag)FLT3LG Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Fms-Related tyrosine Kinase 3 Ligand (FLT3LG) (AA 27-185) protein (His tag)FLT3LG Origin: Human Host: Hi-5 Cells Recombinant >90 % as determined by SDS-PAGE.
Fms-Related tyrosine Kinase 3 Ligand (FLT3LG) (AA 1-235) protein (GST tag)FLT3LG Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Fms-Related tyrosine Kinase 3 Ligand (FLT3LG) protein (His tag)FLT3LG Origin: Mouse Host: Human Cells Recombinant > 95 % as determined by SDS-PAGE
Fms-Related tyrosine Kinase 3 Ligand (FLT3LG) (AA 27-181) protein (His-IF2DI Tag)FLT3LG Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Fms-Related tyrosine Kinase 3 Ligand (FLT3LG) (AA 28-189) protein (His tag)FLT3LG Origin: Mouse Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Fms-Related tyrosine Kinase 3 Ligand (FLT3LG) proteinFLT3LG Origin: Human Host: Escherichia coli (E. coli) Recombinant 98,00% SDS
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Application Notes
- Determined by the dose-dependent stimulation of the proliferation of human AML5 cells. The expected ED50 for this effect is 0,5 - 1 ng/mL.
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Restrictions
- For Research Use only
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- FLT3LG (Fms-Related tyrosine Kinase 3 Ligand (FLT3LG))
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Alternative Name
- Flt-3 Ligand
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Background
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Synonyms: FLT3, FLK2, STK1, CD135, FLK-2
Description: Flt3-ligand (flk2-ligand) stimulates the proliferation and colony formation of certain BM precursor cells including CD34+ cells. Flt3-ligand produced in E. coli is a soluble non-glycosylated 17.6 kDa polypeptide containing 155 amino acid residues which comprises the extracellular domain of the transmembrane flt3-ligand protein.
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Molecular Weight
- 17.6 kDa
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Gene ID
- 2323
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NCBI Accession
- NM_001459, NP_001450
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UniProt
- P49771
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Pathways
- RTK Signaling
Target
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