IL-31 Protein (His tag)

Catalog No. ABIN7884497

This Recombinant IL-31 protein is expressed in Escherichia coli (E. coli).

Quick Overview for IL-31 Protein (His tag) (ABIN7884497)

Target: IL-31 (IL31) (Interleukin 31 (IL31))

Protein Type: Recombinant

Origin: Mouse

Source: Escherichia coli (E. coli)

Application: Western Blotting (WB)

Purity: >98 %

Product Details

Purification tag / Conjugate: This IL-31 protein is labelled with His tag.

Purpose: IL-31 (Interleukin-31), Mouse

Sequence: MTCSLSFGAP ISKEDLRTTI DLLKQESQDL YNNYSIKQAS GMSADESIQL PCFSLDREAL TNISVIIAHL EKVKVLSENT VDTSWVIRWL TNISCF NPLNLNISVP GNTDESYDCK VFVLTVLKQF SNCMAELQAK DNTTC with polyhistid ine tag at the Cterminus

Endotoxin Level: <0.1 EU per 1 μg protein

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: dissolve in sterile H2O

Buffer: PBS, pH 7.4

Storage: -20 °C

Storage Comment: -20°C

Target Details

Target: IL-31 (IL31) (Interleukin 31 (IL31))

Alternative Name: IL-31

Background: Interleukin-31 (IL-31) s an inflammatory cytokine that helps trigger cell-mediated immunity against pathogens. It has also been identified as a major player in a number of chronic inflammatory diseases, including atopic dermatitis. It is produced by a variety of cells, namely type 2 helper (TH2) T-cells. IL-31 sends signals through a receptor complex made of IL-31RA and oncostatin M receptor β (OSMRβ) expressed in immune and epithelial cells. These signals activate three pathways: ERK1/2 MAP kinase, PI3K/AKT, and JAK1/2 signaling pathways.

Molecular Weight: 18kDa

Gene ID: 76399

NCBI Accession: NP_083870

UniProt: Q6EAL8