NOG Protein (His tag)
Quick Overview for NOG Protein (His tag) (ABIN7884551)
Target
See all NOG ProteinsProtein Type
Biological Activity
Origin
Source
Application
Purity
Grade
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Purification tag / Conjugate
- This NOG protein is labelled with His tag.
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Purpose
- Croyez GMP® Noggin, Human
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Sequence
- MQHYLHIRPA PSDNLPLVDL IEHPDPIFDP KEKDLNETLL RSLLGGHYDP GFMATSPPED RPGGGGGAAG GAEDLAELDQ LLRQRPSGAM P SEIKGLEFSE GLAQGKKQRL SKKLRRKLQM WLWSQTFCPV LYAWNDLGSR FWPRYVKVGS CFSKRSCSVP EGMVCKPSKS VHLTVLRWRC QRRGGQRCGW IPIQYPIISE CKCSC with polyhistid ine tag at the C-terminus
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Endotoxin Level
- <0.1 EU per 1 μg protein
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Biological Activity Comment
- ED50 <0.05 μg/mL
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Noggin (NOG) (AA 20-232) (Active) protein
NOG Origin: Mouse Host: CHO Cells Recombinant > 95 % as analyzed by SDS-PAGE. Active
Noggin (NOG) (AA 28-232) (Active) proteinNOG Origin: Human Host: CHO Cells Recombinant > 95 % as analyzed by SDS-PAGE. Active
Noggin (NOG) (AA 28-232) protein (GST tag)NOG Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Noggin (NOG) protein (His tag)NOG Origin: Mouse Host: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Noggin (NOG) protein (Fc Tag)NOG Origin: Human Host: HEK-293 Cells Recombinant Greater than 95 % as determined by reducing SDS-PAGE. AM, ADA, IA, ScA
Noggin (NOG) (AA 28-232) protein (His-IF2DI Tag)NOG Origin: Mouse Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Noggin (NOG) (AA 28-232) protein (Fc Tag)NOG Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- dissolve in sterile H2O
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Buffer
- PBS, pH 7.4
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Storage
- -20 °C
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Storage Comment
- -20°C
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- NOG (Noggin (NOG))
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Alternative Name
- Noggin
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Background
- Noggin is a bioactive protein intended for use in cell culture applications. Noggin protein which bind to ligands of the TGF-β family and regulate their activity by inhibiting their access to signaling receptors. Noggin was originally identified as a BMP-4 antagonist whose action is critical for proper formation of the head and other dorsal structures.
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Molecular Weight
- 26kDa
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Gene ID
- 9241
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NCBI Accession
- NP_005441
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UniProt
- Q13253
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Pathways
- Stem Cell Maintenance, Tube Formation
Target
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