Thyroperoxidase Protein (His tag)
Quick Overview for Thyroperoxidase Protein (His tag) (ABIN7884581)
Target
See all Thyroperoxidase (TPO) ProteinsProtein Type
Origin
Source
Application
Purity
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Purification tag / Conjugate
- This Thyroperoxidase protein is labelled with His tag.
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Purpose
- TPO (Thrombopoietin), Swine
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Sequence
- APPRLICDSR VLERYILEAK EGENATMGCA ESCSFSENIT VPDTKVNFYA WKRMEVQQQA MEVWQGLALL SEAILQGQAL LANSSQPSEA LQ LHVDKAVSGL RSLTSLLRAL GAQKEAIPLP DASPSSATPL RTFAVDTLCK LFRNYSNFLR GKLTLYTGEA CRRRDR with polyhistid ine tag at the N-terminus
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Endotoxin Level
- <0.1 EU per 1 μg protein
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- dissolve in sterile H2O
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Buffer
- PBS, pH 7.4
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Storage
- -20 °C
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Storage Comment
- -20°C
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- Thyroperoxidase (TPO) (Thyroid Peroxidase (TPO))
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Alternative Name
- TPO
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Background
- Thrombopoietin is a glycoprotein hormone produced mainly by the liver and the kidney that regulates the production of platelets by the bone marrow. The protein functions in the iodination of tyrosine residues in thyroglobulin and phenoxy-ester formation between pairs of iodinated tyrosines to generate the thyroid hormones, thyroxine and triiodothyronine. It stimulates the production and differentiation of megakaryocytes, the bone marrow cells that fragment into large numbers of platelets.
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Molecular Weight
- 21kDa
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Gene ID
- 397249
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NCBI Accession
- NP_999299
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UniProt
- P49157
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Pathways
- Thyroid Hormone Synthesis
Target
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