IL-4 Protein

Catalog No. ABIN7956071

This Recombinant IL-4 protein is expressed in Escherichia coli (E. coli).

Quick Overview for IL-4 Protein (ABIN7956071)

Target: IL-4 (IL4) (Interleukin 4 (IL4))

Protein Type: Recombinant

Biological Activity: Active

Origin: Rhesus Monkey

Source: Escherichia coli (E. coli)

Purity: > 96 % by SDS-PAGE and HPLC analyses.

Product Details

Purpose: Recombinant Rhesus Macaque Interleukin-4

Sequence: HNCHIALREI IETLNSLTEQ KTLCTKLTIT DILAASKNTT EKETFCRAAT VLRQFYSHHE KDTRCLGATA QQFHRHKQLI RFLKRLDRNL WGLAGLNSCP VKEANQSTLE DFLERLKTIM REKYSKCSS

Sterility: 0.2 μm filtered

Endotoxin Level: Less than 1 EU/ug of rRhIL-4 as determined by LAL method.

Biological Activity Comment: Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using human TF-1 cells is less than 1.0 ng/ml, corresponding to a specific activity of > 1.0 x10⁶ IU/mg.

Application Details

Comment:

Approximately 14.9 kDa, a single non-glycosylated polypeptide chain containing 129 amino acids.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Lyophilized from a 0.2 um filtered concentrated solution in 2 x PBS, pH 7.4, 5 % trehalose.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.- 12 months from date of receipt, -20 to -70 °C as supplied.- 1 month, 2 to 8 °C under sterile conditions after reconstitution.- 3 months, -20 to -70 °C under sterile conditions after reconstitution.

Expiry Date: 12 months

Target Details

Target: IL-4 (IL4) (Interleukin 4 (IL4))

Alternative Name: Interleukin-4

Molecular Weight: 14.9 kDa

UniProt: P51492

Pathways: JAK-STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Proton Transport, Activated T Cell Proliferation