CNTF Protein
Quick Overview for CNTF Protein (ABIN7937089)
Target
See all CNTF ProteinsProtein Type
Biological Activity
Origin
Source
Purity
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Purpose
- Recombinant Murine Ciliary Neurotrophic Factor
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Sequence
- AFAEQSPLTL HRRDLCSRSI WLARKIRSDL TALMESYVKH QGLNKNISLD SVDGVPVAST DRWSEMTEAE RLQENLQAYR TFQGMLTKLL EDQRVHFTPT EGDFHQAIHT LTLQVSAFAY QLEELMALLE QKVPEKEADG MPVTIGDGGL FEKKLWGLKV LQELSQWTVR SIHDLRVISS HHMGISAHES HYGAKQM
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Sterility
- 0.2 μm filtered
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Endotoxin Level
- Less than 1 EU/ug of rMuCNTF as determined by LAL method.
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Biological Activity Comment
- Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using human TF-1 cells is less than 30 ng/ml, corresponding to a specific activity of > 3.3 x104 IU/mg.
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Comment
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Approximately 22.5 kDa, a single non-glycosylated polypeptide chain containing 197 amino acids.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- Lyophilized from a 0.2 um filtered concentrated solution in 20 mM PB, pH 7.4, 150 mM NaCl, with 5 % Trehalose, 0.02 % Tween-20.
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Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles.- 12 months from date of receipt, -20 to -70 °C as supplied.- 1 month, 2 to 8 °C under sterile conditions after reconstitution.- 3 months, -20 to -70 °C under sterile conditions after reconstitution.
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Expiry Date
- 12 months
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- CNTF (Ciliary Neurotrophic Factor (CNTF))
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Alternative Name
- Ciliary Neurotrophic Factor
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Molecular Weight
- 22.5 kDa
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Gene ID
- 12803
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UniProt
- P51642
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Pathways
- JAK-STAT Signaling
Target
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