GM-CSF Protein

Catalog No. ABIN7937095

Recombinant GM-CSF protein expressed in Escherichia coli (E. coli).

Quick Overview for GM-CSF Protein (ABIN7937095)

Target: GM-CSF (CSF2) (Colony Stimulating Factor 2 (Granulocyte-Macrophage) (CSF2))

Protein Type: Recombinant

Biological Activity: Active

Origin: Dog

Source: Escherichia coli (E. coli)

Purity: > 95 % by SDS-PAGE and HPLC analyses.

Product Details

Purpose: Recombinant Canine Granulocyte-Macrophage Colony Stimulating Factor

Sequence: APTRSPTLVT RPSQHVDAIQ EALSLLNNSN DVTAVMNKAV KVVSEVFDPE GPTCLETRLQ LYKEGLQGSL TSLKNPLTMM ANHYKQHCPP TPESPCATQN INFKSFKENL KDFLFNIPFD CWKPVKK

Sterility: 0.2 μm filtered

Endotoxin Level: Less than 1 EU/ug of rCaGM-CSF as determined by LAL method.

Biological Activity Comment: Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using human TF-1 cells is less than 5 ng/ml, corresponding to a specific activity of > 2.0 x10⁵ IU/mg.

Application Details

Comment:

Approximately 14.2 kDa, a single non-glycosylated polypeptide chain containing 127 amino acids.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Lyophilized from a 0.2 um filtered concentrated solution in PBS, pH 7.4.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.- 12 months from date of receipt, -20 to -70 °C as supplied.- 1 month, 2 to 8 °C under sterile conditions after reconstitution.- 3 months, -20 to -70 °C under sterile conditions after reconstitution.

Expiry Date: 12 months

Target Details

Target: GM-CSF (CSF2) (Colony Stimulating Factor 2 (Granulocyte-Macrophage) (CSF2))

Alternative Name: Granulocyte-Macrophage Colony Stimulating Factor

Molecular Weight: 14.2 kDa

Gene ID: 403923

UniProt: P48749

Pathways: JAK-STAT Signaling, Cellular Response to Molecule of Bacterial Origin