Amphiregulin Protein (AREG)
Quick Overview for Amphiregulin Protein (AREG) (ABIN7937127)
Target
See all Amphiregulin (AREG) ProteinsProtein Type
Biological Activity
Origin
Source
Purity
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Purpose
- Recombinant Human Amphiregulin
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Sequence
- SVRVEQVVKP PQNKTESENT SDKPKRKKKG GKNGKNRRNR KKKNPCNAEF QNFCIHGECK YIEHLEAVTC KCQQEYFGER CGEKSMKTHS MIDSSLSK
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Sterility
- 0.2 μm filtered
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Endotoxin Level
- Less than 1 EU/ug of rHuAmphiregulin as determined by LAL method.
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Biological Activity Comment
- Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using murine Balb/c 3T3 cells is between 5-10 ng/ml.
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Amphiregulin (AREG) (Active) protein
AREG Origin: Human Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS-PAGE Func Active
Amphiregulin (AREG) (AA 101-187) (Active) protein (hFc Tag)AREG Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Amphiregulin (AREG) (AA 100-248) (Active) protein (hFc Tag)AREG Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Amphiregulin (AREG) (AA 1-252) protein (GST tag)AREG Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Amphiregulin (AREG) (AA 20-187) protein (Fc Tag)AREG Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. ScA, IA, ADA, AM
Amphiregulin (AREG) (AA 101-198) protein (His tag)AREG Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
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Comment
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Approximately 11.3 kDa, a single non-glycosylated polypeptide chain containing 98 amino acid residues.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- Lyophilized from a 0.2 um filtered concentrated solution in PBS, pH 7.4.
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Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles.- 12 months from date of receipt, -20 to -70 °C as supplied.- 1 month, 2 to 8 °C under sterile conditions after reconstitution.- 3 months, -20 to -70 °C under sterile conditions after reconstitution.
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Expiry Date
- 12 months
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- Amphiregulin (AREG)
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Alternative Name
- Amphiregulin
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Molecular Weight
- 11.3 kDa
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Gene ID
- 374
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UniProt
- P15514
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Pathways
- RTK Signaling, EGFR Signaling Pathway
Target
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