IL12A Protein
This Recombinant IL12A protein is expressed in Mammalian Cells.
Catalog No. ABIN7937193
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Quick Overview for IL12A Protein (ABIN7937193)
Target
See all IL12A Proteins
IL12A
(Interleukin 12 alpha (IL12A))
Protein Type
Recombinant
Biological Activity
Active
Origin
Human
Source
Mammalian Cells
Purity
>95 % as determined by SDS-PAGE and HPLC.
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Purpose
- Recombinant Human Interleukin-12 subunit alpha protein(IL12A) (Active)
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Sequence
- p35 Subunit: RNLPVATPDP GMFPCLHHSQ NLLRAVSNML QKARQTLEFY PCTSEEIDHE DITKDKTSTV EACLPLELTK NESCLNSRET SFITNGSCLA SRKTSFMMAL CLSSIYEDLK MYQVEFKTMN AKLLMDPKRQ IFLDQNMLAV IDELMQALNF NSETVPQKSS LEEPDFYKTK IKLCILLHAF RIRAVTIDRV MSYLNAS p40 Subunit: IWELKKDVYV VELDWYPDAP GEMVVLTCDT PEEDGITWTL DQSSEVLGSG KTLTIQVKEF GDAGQYTCHK GGEVLSHSLL LLHKKEDGIW STDILKDQKE PKNKTFLRCE AKNYSGRFTC WWLTTISTDL TFSVKSSRGS SDPQGVTCGA ATLSAERVRG DNKEYEYSVE CQEDSACPAA EESLPIEVMV DAVHKLKYEN YTSSFFIRDI IKPDPPKNLQ LKPLKNSRQV EVSWEYPDTW STPHSYFSLT FCVQVQGKSK REKKDRVFTD KTSATVICRK NASISVRAQD RYYSSSWSEW ASVPCS
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Sterility
- 0.2 μm filtered
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Biological Activity Comment
- Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using PHA-activated human T lymphoblasts is less than 0.05 ng,ml, corresponding to a specific activity of 2.0 107 IU,mg.
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Interleukin 12 alpha (IL12A) (AA 144-253) protein (GST tag)
IL12A Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
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Comment
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75.0 kDa
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- 0.2 um filtered PBS, pH 7.4 ,lyophilized
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Handling Advice
- Repeated freezing and thawing is not recommended
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Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
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The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C,-80°C. The shelf life of lyophilized form is 12 months at -20°C,-80°C.
Notes:Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week. -
Expiry Date
- 12 months
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- IL12A (Interleukin 12 alpha (IL12A))
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Alternative Name
- Interleukin-12 subunit alpha
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Molecular Weight
- 75.0 kDa
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Gene ID
- 3592
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UniProt
- P29459
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Pathways
- JAK-STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation
Target
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