Neuregulin 1 Protein (NRG1)

Catalog No. ABIN7957086

This Recombinant Neuregulin 1 protein is produced in Escherichia coli (E. coli).

Quick Overview for Neuregulin 1 Protein (NRG1) (ABIN7957086)

Target: Neuregulin 1 (NRG1)

Protein Type: Recombinant

Biological Activity: Active

Origin: Human

Source: Escherichia coli (E. coli)

Purity: >97 % as determined by SDS-PAGE and HPLC.

Product Details

Purpose: Recombinant Human Pro-neuregulin-1, membrane-bound isoform protein(NRG1) (Active)

Sequence: SHLVKCAEKE KTFCVNGGEC FMVKDLSNPS RYLCKCPNEF TGDRCQNYVM ASFYKHLGIE FMEAE

Biological Activity Comment: Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using serum free human MCF-7 cells is less than 0.5 ng,ml, corresponding to a specific activity of 2.0 106 IU,mg.

Application Details

Comment:

7.5 kDa

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.2 m filtered 1 PBS, pH 7.4, with 5 % trehalose ,lyophilized

Handling Advice: Repeated freezing and thawing is not recommended

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C,-80°C. The shelf life of lyophilized form is 12 months at -20°C,-80°C.
Notes:Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Expiry Date: 12 months

Target Details

Target: Neuregulin 1 (NRG1)

Alternative Name: Pro-neuregulin-1

Molecular Weight: 7.5 kDa

Gene ID: 3084

UniProt: Q02297

Pathways: RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Muscle Cell Differentiation