FAS Protein (Soluble)
Quick Overview for FAS Protein (Soluble) (ABIN7955942)
Target
See all FAS ProteinsProtein Type
Biological Activity
Origin
Source
Purity
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Protein Characteristics
- Soluble
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Purpose
- Recombinant Human soluble Fas Receptor/TNFRSF6
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Sequence
- RLSSKSVNAQ VTDINSKGLE LRKTVTTVET QNLEGLHHDG QFCHKPCPPG ERKARDCTVN GDEPDCVPCQ EGKEYTDKAH FSSKCRRCRL CDEGHGLEVE INCTRTQNTK CRCKPNFFCN STVCEHCDPC TKCEHGIIKE CTLTSNTKCK EEGSRSN
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Sterility
- 0.2 μm filtered
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Endotoxin Level
- Less than 1 EU/ug of rHusFasR/TNFRSF6 as determined by LAL method.
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Biological Activity Comment
- Fully biologically active when compared to standard. The ED50 as determined by its ability to inhibit the cytotoxicity of Jurkat cells is between 10-15 μg/ml in the presence of 2 ng/ml of rHuFas Ligand.
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TNF Receptor Superfamily, Member 6 (FAS) (AA 25-169) protein (His-DYKDDDDK-Strep II Tag)
FAS Origin: Human Host: HEK-293T Cells Recombinant WB, SDS, ELISA, PI
TNF Receptor Superfamily, Member 6 (FAS) (AA 17-173) protein (His tag)FAS Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
TNF Receptor Superfamily, Member 6 (FAS) (Active) protein (His tag)FAS Origin: Rat Host: HEK-293 Cells Recombinant > 90 % as determined by SDS-PAGE Active
TNF Receptor Superfamily, Member 6 (FAS) protein (His tag)FAS Origin: Mouse Host: Human Cells Recombinant > 95 % as determined by SDS-PAGE
TNF Receptor Superfamily, Member 6 (FAS) (Active) protein (His tag)FAS Origin: Mouse Host: HEK-293 Cells Recombinant > 98 % as determined by SDS-PAGE Active
TNF Receptor Superfamily, Member 6 (FAS) protein (Fc Tag)FAS Origin: Mouse Host: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
TNF Receptor Superfamily, Member 6 (FAS) (AA 26-173) (Active) protein (His tag)FAS Origin: Human Host: Baculovirus infected Insect Cells Recombinant > 95 % SDS, AcA Active
TNF Receptor Superfamily, Member 6 (FAS) (AA 26-173) protein (Fc Tag)FAS Origin: Human Host: Mammalian Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
TNF Receptor Superfamily, Member 6 (FAS) (AA 1-335) protein (GST tag)FAS Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
TNF Receptor Superfamily, Member 6 (FAS) (AA 26-173) (Active) protein (Fc Tag)FAS Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
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Comment
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Approximately 17.6 kDa, a single non-glycosylated polypeptide chain containing 157 amino acids.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- Lyophilized from a 0.2 um filtered concentrated solution in PBS, pH 7.4.
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Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles.- 12 months from date of receipt, -20 to -70 °C as supplied.- 1 month, 2 to 8 °C under sterile conditions after reconstitution.- 3 months, -20 to -70 °C under sterile conditions after reconstitution.
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Expiry Date
- 12 months
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- FAS (TNF Receptor Superfamily, Member 6 (FAS))
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Alternative Name
- Fas Receptor
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Molecular Weight
- 17.6 kDa
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Gene ID
- 355
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UniProt
- P25445
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Pathways
- p53 Signaling, Apoptosis, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity
Target
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