Neurotrophin 4 Protein (NTF4)

Catalog No. ABIN7937358

This Recombinant Neurotrophin 4 protein is expressed in Escherichia coli (E. coli).

Quick Overview for Neurotrophin 4 Protein (NTF4) (ABIN7937358)

Target: Neurotrophin 4 (NTF4)

Protein Type: Recombinant

Biological Activity: Active

Origin: Human

Source: Escherichia coli (E. coli)

Purity: > 97 % by SDS-PAGE and HPLC analyses.

Product Details

Purpose: Recombinant Human Neurotrophin-4

Sequence: MGVSETAPAS RRGELAVCDA VSGWVTDRRT AVDLRGREVE VLGEVPAAGG SPLRQYFFET RCKADNAEEG GPGAGGGGCR GVDRRHWVSE CKAKQSYVRA LTADAQGRVG WRWIRIDTAC VCTLLSRTGR A

Sterility: 0.2 μm filtered

Endotoxin Level: Less than 1 EU/ug of rHuNT-4 as determined by LAL method.

Biological Activity Comment: Fully biologically active when compared to standard. The ED50 as determined by the dose-dependent induction of choline acetyl transferase activity in rat basal forebrain primary septal cell cultures is less than 50 ng/ml, corresponding to a specific activity of > 2.0 x10⁴ IU/mg.

Application Details

Comment:

Approximately 28.1 kDa, a noncovalently linked homodimer of two 14.0 kDa polypeptide monomers (262 total amino acid residues).

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Lyophilized from a 0.2 um filtered concentrated solution in PBS, pH 5.5.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.- 12 months from date of receipt, -20 to -70 °C as supplied.- 1 month, 2 to 8 °C under sterile conditions after reconstitution.- 3 months, -20 to -70 °C under sterile conditions after reconstitution.

Expiry Date: 12 months

Target Details

Target: Neurotrophin 4 (NTF4)

Alternative Name: Neurotrophin-4

Molecular Weight: 28.1 kDa,14.0 kDa

Gene ID: 4909

UniProt: P34130

Pathways: RTK Signaling