FGF23 Protein
Quick Overview for FGF23 Protein (ABIN7937380)
Target
See all FGF23 ProteinsProtein Type
Biological Activity
Origin
Source
Purity
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Purpose
- Recombinant Human Fibroblast Growth Factor 23
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Sequence
- YPNASPLLGS SWGGLIHLYT ATARNSYHLQ IHKNGHVDGA PHQTIYSALM IRSEDAGFVV ITGVMSRRYL CMDFRGNIFG SHYFDPENCR FQHQTLENGY DVYHSPQYHF LVSLGRAKRA FLPGMNPPPY SQFLSRRNEI PLIHFNTPIP RRHTRSAEDD SERDPLNVLK PRARMTPAPA SCSQELPSAE DNSPMASDPL GVVRGGRVNT HAGGTGPEGC RPFAKFI
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Sterility
- 0.2 μm filtered
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Endotoxin Level
- Less than 1 EU/ug of rHuFGF-23 as determined by LAL method.
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Biological Activity Comment
- Fully biologically active when compared to standard. The ED50 as determined by thymidine uptake assay using FGF-receptors transfected BaF3 cells is less than 0.5 μg/ml, corresponding to a specific activity of > 2.0 x103 IU/mg in the presence of 0.3 μg/ml of rMuKlotho and 10 μg/ml of heparin.
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Comment
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Approximately 25.3 kDa, a single non-glycosylated polypeptide chain containing 227 amino acids.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- Lyophilized from a 0.2 um filtered concentrated solution in PBS, pH 7.4.
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Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles.- 12 months from date of receipt, -20 to -70 °C as supplied.- 1 month, 2 to 8 °C under sterile conditions after reconstitution.- 3 months, -20 to -70 °C under sterile conditions after reconstitution.
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Expiry Date
- 12 months
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- FGF23 (Fibroblast Growth Factor 23 (FGF23))
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Alternative Name
- Fibroblast Growth Factor 23
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Molecular Weight
- 25.3 kDa
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Gene ID
- 8074
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UniProt
- Q9GZV9
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Pathways
- RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Negative Regulation of Hormone Secretion
Target
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