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FGF21 Protein

This Recombinant FGF21 protein is produced in Escherichia coli (E. coli).
Catalog No. ABIN7955971
$1,013.10
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Quick Overview for FGF21 Protein (ABIN7955971)

Target

See all FGF21 Proteins
FGF21 (Fibroblast Growth Factor 21 (FGF21))

Protein Type

Recombinant

Biological Activity

Active

Origin

  • 36
  • 17
  • 4
  • 4
  • 2
  • 1
  • 1
  • 1
Human

Source

  • 30
  • 17
  • 5
  • 4
  • 3
  • 2
  • 1
  • 1
  • 1
Escherichia coli (E. coli)

Purity

> 96 % by SDS-PAGE and HPLC analyses.
  • Purpose

    Recombinant Human Fibroblast Growth Factor 21

    Sequence

    HPIPDSSPLL QFGGQVRQRY LYTDDAQQTE AHLEIREDGT VGGAADQSPE SLLQLKALKP GVIQILGVKT SRFLCQRPDG ALYGSLHFDP EACSFRELLL EDGYNVYQSE AHGLPLHLPG NKSPHRDPAP RGPARFLPLP GLPPALPEPP GILAPQPPDV GSSDPLSMVG PSQGRSPSYA S

    Sterility

    0.2 μm filtered

    Endotoxin Level

    Less than 1 EU/ug of rHuFGF-21 as determined by LAL method.

    Biological Activity Comment

    Fully biologically active when compared to standard. The ED50 as determined by thymidine uptake assay using FGF-receptors transfected BaF3 cells is less than 0.5 μg/ml, corresponding to a specific activity of > 2.0 x103 IU/mg in the presence of 5 μg/ml of rMuKlotho-β, and 10 μg/ml of heparin.
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  • Comment

    Approximately 19.4 kDa, a single non-glycosylated polypeptide chain containing 181 amino acids.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Buffer

    Lyophilized from a 0.2 um filtered concentrated solution in PBS, pH 7.4.

    Storage

    4 °C,-20 °C,-80 °C

    Storage Comment

    Use a manual defrost freezer and avoid repeated freeze-thaw cycles.- 12 months from date of receipt, -20 to -70 °C as supplied.- 1 month, 2 to 8 °C under sterile conditions after reconstitution.- 3 months, -20 to -70 °C under sterile conditions after reconstitution.

    Expiry Date

    12 months
  • Target

    FGF21 (Fibroblast Growth Factor 21 (FGF21))

    Alternative Name

    Fibroblast Growth Factor 21

    Molecular Weight

    19.4 kDa

    Gene ID

    26291

    UniProt

    Q9NSA1

    Pathways

    RTK Signaling
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