IL-6 Receptor Protein (AA 20-358, Subunit alpha)
Quick Overview for IL-6 Receptor Protein (AA 20-358, Subunit alpha) (ABIN7955874)
Target
See all IL-6 Receptor (IL6R) ProteinsProtein Type
Biological Activity
Origin
Source
Purity
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Protein Characteristics
- AA 20-358, Subunit alpha
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Purpose
- Recombinant Human Interleukin-6 Receptor Subunit Alpha
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Sequence
- Leu20-Asp358,
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Sterility
- 0.2 μm filtered
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Endotoxin Level
- Less than 1 EU/ug of rHuIL-6 Ralpha as determined by LAL method.
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Biological Activity Comment
- Measured by its ability to enhance the IL-6 activity on M1 mouse myeloid leukemia cells. The ED50 for this effect is 5-15 ng/ml.
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Interleukin 6 Receptor (IL6R) (AA 20-365) (Active) protein (His tag)
IL6R Origin: Rhesus Monkey Host: Mammalian Cells Recombinant Greater than 95 % as determined by SDS-PAGE. Greater than 90 % as determined by SEC-HPLC. Active
Interleukin 6 Receptor (IL6R) (AA 20-365) protein (His tag)IL6R Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. AM, ADA, IA, ScA
Interleukin 6 Receptor (IL6R) (AA 20-365) protein (Fc Tag)IL6R Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. AM, ADA, IA, ScA
Interleukin 6 Receptor (IL6R) (AA 229-468) protein (His-IF2DI Tag)IL6R Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Interleukin 6 Receptor (IL6R) (AA 1-468) protein (GST tag)IL6R Origin: Human Host: Wheat germ Recombinant AP, AA, ELISA, WB
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Comment
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Apparent molecular mass of 45-50 kDa in SDS-PAGE under reducing conditions, a single glycosylated polypeptide protein consisting of 339 amino acids.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- Lyophilized from 0.2 um filtered concentrated solution in PBS.
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Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. -12 months from date of receipt, -20 to -70 °C as supplied. -1 month, 2 to 8 °C under sterile conditions after reconstitution. -3 months, -20 to -70 °C under sterile conditions after reconstitution.
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Expiry Date
- 12 months
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- IL-6 Receptor (IL6R) (Interleukin 6 Receptor (IL6R))
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Alternative Name
- Interleukin-6 Receptor
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Molecular Weight
- 50 kDa
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Pathways
- JAK-STAT Signaling, Autophagy, Growth Factor Binding, Cancer Immune Checkpoints
Target
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