CTBP1 Protein
Quick Overview for CTBP1 Protein (ABIN7938667)
Target
See all CTBP1 ProteinsProtein Type
Origin
Source
Application
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Purpose
- Recombinant CTBP1 protein
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Characteristics
- CTBP1 (C-Terminal Binding Protein 1), also written as CtBP1, is a protein that binds to the C-terminus of adenovirus E1A proteins. This phosphoprotein is a transcriptional repressor and may play a role during cellular proliferation. It is a corepressor targeting diverse transcription regulators such as GLIS2 or BCL6. It also has dehydrogenase activity. It is involved in controlling the equilibrium between tubular and stacked structures in the Golgi complex, and has functions in brown adipose tissue (BAT) differentiation.
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C-terminal Binding Protein 1 (CTBP1) (AA 1-440) protein
CTBP1 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % pure SDS
C-terminal Binding Protein 1 (CTBP1) (AA 1-429) protein (GST tag)CTBP1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
C-terminal Binding Protein 1 (CTBP1) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)CTBP1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
C-terminal Binding Protein 1 (CTBP1) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)CTBP1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Recombinant CTBP1 protein is supplied in 25 mM Tris-HCl pH 8.0, 500 mM NaCl, 10 % glycerol, 0.5 mM TCEP.
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Handling Advice
- Avoid repeated freeze/thaw cycles,keep on ice when not in storage
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Storage
- -80 °C
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Storage Comment
- Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
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- CTBP1 (C-terminal Binding Protein 1 (CTBP1))
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Alternative Name
- CTBP1
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Background
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Protein Background: CTBP1 (C-Terminal Binding Protein 1), also written as CtBP1, is a protein that binds to the C-terminus of adenovirus E1A proteins. This phosphoprotein is a transcriptional repressor and may play a role during cellular proliferation. It's a corepressor targeting diverse transcription regulators such as GLIS2 or BCL6. It also has dehydrogenase activity. Involved in controlling the equilibrium between tubular and stacked structures in the Golgi complex. Functions in brown adipose tissue (BAT) differentiation.
Short Description: Recombinant CTBP1 protein was expressed in E.coli as the full length protein (accession number (NP_001319.1) with an N-terminal 6x-His Tag. The molecular weight of the protein is 51.1 kDa.
Aliases: C-terminal Binding Protein, BARS
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Pathways
- Retinoic Acid Receptor Signaling Pathway
Target
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