CHD7 Protein
Quick Overview for CHD7 Protein (ABIN7938717)
Target
Protein Type
Origin
Source
Application
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Purpose
- Recombinant CHD7 protein
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Recombinant CHD7 protein is supplied in 25 mM HEPES pH 7.5, 300 mM NaCl, 20 % glycerol, 0.04 % Triton X-100, 0.5 mM TCEP.
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Handling Advice
- Avoid repeated freeze/thaw cycles,keep on ice when not in storage
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Storage
- -80 °C
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Storage Comment
- Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
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- CHD7 (Chromodomain Helicase DNA Binding Protein 7 (CHD7))
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Alternative Name
- CHD7
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Background
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Protein Background: CHD7 is one of the nine members of the chromodomain helicase DNA-binding family of ATP-dependent chromatin remodeling enzymes. CHD proteins are broadly classified into three subfamilies on the basis of their constituent domains: subfamily I (CHD1 and CHD2), subfamily II (CHD3, CHD4 and CHD5) and sub-family III (CHD6, CHD7, CHD8 and CHD9). CHD7 is the most extensively studied member of CHD subfamily III. Mutations in CHD7 give rise to CHARGE syndrome, a human condition characterized by malformation of various organs.
Short Description: Recombinant CHD7 protein was expressed in a baculovirus expression system as the full-length protein (accession number NP_060250.2) with an N-terminal FLAG tag. The molecular weight of CHD7 is 337.2 kDa.
Aliases: CRG, KAL5, HH5, IS3, Chromodomain Helicase DNA binding protein 7
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Pathways
- Sensory Perception of Sound, Chromatin Binding
Target
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