MRM1 Protein

Catalog No. ABIN7939318

This Recombinant MRM1 protein is expressed in Escherichia coli (E. coli).

Quick Overview for MRM1 Protein (ABIN7939318)

Target: MRM1 (Mitochondrial rRNA Methyltransferase 1 Homolog (MRM1))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Application: Activity Assay (AcA), Functional Studies (Func), Screening Assay (ScA)

Product Details

Purpose: Recombinant MRM1 protein

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Recombinant MRM1 protein is supplied in 25 mM Tris 8.0, 300 mM NaCl, 20 % glycerol, 0.5 mM TCEP.

Handling Advice: Avoid repeated freeze/thaw cycles,keep on ice when not in storage

Storage: -80 °C

Storage Comment: Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

Target Details

Target: MRM1 (Mitochondrial rRNA Methyltransferase 1 Homolog (MRM1))

Alternative Name: MRM1

Background:

Protein Background: MRM1(rRNA methyltransferase 1, mitochondrial) is a S-adenosyl-L-methionine-dependent 2'-O-ribose methyltransferase that catalyzes the formation of 2'-O-methylguanosine at position 1145 (Gm1145) in the 16S mitochondrial large subunit ribosomal RNA (mtLSU rRNA), a universally conserved modification in the peptidyl transferase domain of the mtLSU rRNA.

Short Description: Recombinant MRM1 protein that includes full length of human MRM1 protein (accession number NP_079140.2) was expressed was expressed in E. coli cells with an N-terminal GST tag. The molecular weight of the protein is 65.47 kDa.

Aliases: Mitochondrial rRNA Methyltransferase 1, RRNA Methyltransferase, MRM1 (FLJ22578)