N6AMT1 Protein
Quick Overview for N6AMT1 Protein (ABIN7939361)
Target
See all N6AMT1 ProteinsProtein Type
Origin
Source
Application
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Purpose
- Recombinant N6AMT1 protein
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N-6 Adenine-Specific DNA Methyltransferase 1 (Putative) (N6AMT1) (AA 1-214) protein (His tag)
custom-made N6AMT1 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
N-6 Adenine-Specific DNA Methyltransferase 1 (Putative) (N6AMT1) (AA 1-186) protein (GST tag)N6AMT1 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
N-6 Adenine-Specific DNA Methyltransferase 1 (Putative) (N6AMT1) (AA 1-214) protein (His tag)N6AMT1 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 85 % SDS
N-6 Adenine-Specific DNA Methyltransferase 1 (Putative) (N6AMT1) (AA 1-214) protein (His-IF2DI Tag)N6AMT1 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. ELISA, WB
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Recombinant N6AMT1 protein is supplied in 25 mM Tris-HCl pH 8.0, 300 mM NaCl, 10 % glycerol and 0.5 mM TCEP.
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Handling Advice
- Avoid repeated freeze/thaw cycles,keep on ice when not in storage
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Storage
- -80 °C
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Storage Comment
- Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
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- N6AMT1 (N-6 Adenine-Specific DNA Methyltransferase 1 (Putative) (N6AMT1))
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Alternative Name
- N6AMT1
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Background
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Protein Background: DNA N6-methyladenosine (6mA) is a novel epigenetic signaling modification in humans and has been implicated in the progression and tumorigenesis of several cancers. However, the function and mechanism of 6mA in breast cancer (BC), the most common cancer among women are unclear.N6AMT1(N-6 adenine-specific DNA methyltransferase 1) encodes an N(6)-adenine-specific DNA methyltransferase. The encoded enzyme may be involved in the methylation of release factor I during translation termination. This enzyme is also involved in converting the arsenic metabolite monomethylarsonous acid to the less toxic dimethylarsonic acid. Alternative splicing pf this gene results in multiple transcript variants.
Short Description: Recombinant N6AMT1 protein that includes full length of human N6AMT1 protein (accession number NP_037372.4) was expressed was expressed in E. coli cells with an N-terminal GST tag. The molecular weight of the protein is 49.79 kDa.
Aliases: DNA N6-methyladenosine, N-6-Adenine-Specific DNA Methyltransferase 1, PRED28, KMT9, N6AMT, HEMK2, MTQ2, PRMC
Target
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